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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2021-20-2-28-41</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-1223</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Влияние вакцинации против гриппа и пневмококковой инфекции на заболеваемость населения острыми респираторными вирусными инфекциями и внебольничными пневмониями в Центральном административном округе Москвы</article-title><trans-title-group xml:lang="en"><trans-title>The impact of vaccination against influenza and pneumococcal infection on the incidence of acute respiratory viral infections and community-acquired pneumonia in the Central Administrative District of Moscow</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1738-0850</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gruzdeva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Александровна Груздева,  д. м. н., кафедра эпидемиологии и современных технологий вакцинации Института профессионального образования Первого МГМУ имени И. М. Сеченова (Сеченовский Университет), главный врач филиала ФБУЗ «Центр гигиены и эпидемиологии в ЦАО города Москвы»</p><p>Москва</p></bio><bio xml:lang="en"><p>Olga A. Gruzdeva, Dr. Sci. (Med.), Department of Epidemiology and Modern Vaccination Technologies of Sechenov University, Chief Physician of Center of Hygiene and Epidemiology in Moscow, branch in the Central Administrative District of Moscow</p><p>Moscow</p></bio><email xlink:type="simple">gruzdeva_oa@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3138-3625</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Биличенко</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bilichenko</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Николаевна Биличенко, д. м. н., профессор, заведующая лабораторией клинической эпидемиологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Tatyana N. Bilichenko, Dr. Sci. (Med.), Professor, Head of the Laboratory of Clinical Epidemiology of Research Institute of Pulmonology</p><p>Moscow</p></bio><email xlink:type="simple">tbilichenko@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9061-8247</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барышев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baryshev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михаил Алексеевич Барышев, врач-эпидемиолог эпидемиологического отдела</p><p>Москва</p></bio><bio xml:lang="en"><p>Mikhail A. Baryshev, epidemiologist of the epidemiological Department of Center of Hygiene and Epidemiology in Moscow, branch in the Central Administrative District of Moscow</p><p>Moscow</p></bio><email xlink:type="simple">m.a.baryshev@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасия Валерьевна Жукова, врач-бактериолог микробиологической лаборатории филиала ФБУЗ «Центр гигиены и эпидемиологии в городе Москве» в ЦАО города Москвы, аспирант кафедры микробиологии, вирусологии и иммунологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Anastasia V. Zhukova, doctor-bacteriologist of the Microbiological Laboratory of Center for Hygiene and Epidemiology in Moscow, a branch in the Central Administrative District of Moscow; post-graduate student of the Department of Microbiology, Virology and Immunology of Sechenov University</p><p>Moscow</p></bio><email xlink:type="simple">anastasiagos1@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в городе Москве», филиал в ЦАО города Москвы; ФГАОУ ВО Первый Московский государственный медицинский университет имени И. М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Hygiene and Epidemiology in Moscow branch in the Central Administrative District of Moscow; Sechenov University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НИИ пульмонологии» ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pulmonology of the Federal Medical and Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в городе Москве», филиал в ЦАО города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Hygiene and Epidemiology in Moscow branch in the Central Administrative District of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>02</day><month>05</month><year>2021</year></pub-date><volume>20</volume><issue>2</issue><fpage>28</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Груздева О.А., Биличенко Т.Н., Барышев М.А., Жукова А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Груздева О.А., Биличенко Т.Н., Барышев М.А., Жукова А.В.</copyright-holder><copyright-holder xml:lang="en">Gruzdeva O.A., Bilichenko T.N., Baryshev M.A., Zhukova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/1223">https://www.epidemvac.ru/jour/article/view/1223</self-uri><abstract><p>Актуальность. Острые респираторные вирусные инфекции (ОРВИ) и пневмококковые инфекции (ПИ) ежегодно наносят большой ущерб здоровью и трудоспособности населения, приводят к экономическим потерям работодателей и государства. Цель. Изучить влияние охвата вакцинацией против гриппа и ПИ на заболеваемость ОРВИ и внебольничной пневмонией (ВП) населения Центрального административного округа (ЦАО) Москвы. Материал и методы. Анализ официальных данных о заболеваемости населения ОРВИ и ВП в ЦАО и информации о вакцинации против гриппа и ПИ в 2012–2018 гг. Результаты. В структуре инфекционной заболеваемости населения ЦАО в 2018 г. ОРВИ составили 95,2%, а показатель заболеваемости – 29 853,5 на 100 тыс. населения. В 2012–2018 гг. заболеваемость ОРВИ и гриппом постепенно снижалась к 2016 г., но в 2017 г. вновь был отмечен подъем до уровня 2012 г. за счет ОРВИ (+25,3%), а заболеваемость гриппом снизилась (-40,9%). В 2018 г. заболеваемость ОРВИ у взрослых сохранялась на уровне 2017 г., а у детей отмечено снижение на 16,9%. Заболеваемость гриппом в 2018 г. снизилась как у взрослых (-65,4%), так и у детей (-63,9%). Заболеваемость ВП на протяжении всего периода имела стойкую тенденцию к росту. Охват вакцинацией против гриппа населения ЦАО с 2012 г. ежегодно увеличивался и в 2018 г. достиг у детей 0–17 лет 85,5% и взрослых 18 лет и старше – 65,5%, и против ПИ – 46,3 и 2,6% соответственно. Заключение. Эпидемическая циркуляция вирусов ОРВИ и гриппа в 2012–2018 гг. сохраняла влияние на инфекционную заболеваемость населения ЦАО. Ежегодная вакцинация населения ЦАО способствовала снижению заболеваемости гриппом, но заболеваемость пневмонией имела тенденцию к увеличению, что указывает на необходимость совершенствования ее профилактики.</p></abstract><trans-abstract xml:lang="en"><p>Background. Acute respiratory viral infections (ARVI) and pneumococcal infections (PI) annually cause great damage to the health and working capacity of the population, and lead to economic losses for employers and the state. Aim. To study the impact of influenza and PI vaccination coverage on morbidity of ARVI and community-acquired pneumonia (CAP) of the morbidity of population in Central administrative district (CAD) of Moscow. Material and methods. The analysis of official data on monitoring of morbidity from ARVI and CAP was carried out, and information on vaccination of the population against influenza and PI for 2012–2018 was used. Results. In 2018 ARVI accounted for 95.2% of infectious morbidity and the incidence rate was 29853.5 per 100 ths population. Over the period from 2012–2018, the incidence of ARVI and influenza gradually decreased by 2016, but in 2017 the incidence of ARVI was increased to the level of 2012 (+25.3%) however influenza was decreased (-40.9%). In 2018, the incidence of ARVI in adults remained at the level of 2017, and in children there was a decrease (-16.9%). The incidence of influenza in 2018 decreased in both adults (-65.4%) and children (-63.9%). During 2012–2018 the incidence of CAP had a persistent tendency to increase. The coverage of influenza vaccination in CAD population of Moscow has increased annually since 2012 and in 2018 reached 85.5% of children 0–17 years old and 65.5% of adults 18 years and older, and against PI – 46.3% of children and 2.6% of adults. Conclusion. The epidemic circulation of ARVI and influenza had a significant impact on the morbidity of CAD population of Moscow in 2012–2018. Annual vaccination of the population lead to decreasing of influenza incidence but the incidence of pneumonia tended to increase and need to improve prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпидемиология</kwd><kwd>вакцинация</kwd><kwd>грипп</kwd><kwd>пневмококковая инфекция</kwd><kwd>заболеваемость</kwd><kwd>летальность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epidemiology</kwd><kwd>vaccination</kwd><kwd>influenza</kwd><kwd>pneumococcal infection</kwd><kwd>morbidity</kwd><kwd>mortality</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2017 году: Государственный доклад.– М.: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека, 2018.–268 с. 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