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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2016-15-1-39-43</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-124</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНФОРМАЦИЯ ВОЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>WHO INFORMATION</subject></subj-group></article-categories><title-group><article-title>Изучение серопревалентности вируса гепатита Е в различных возрастных группах здорового населения Кыргызстана</article-title><trans-title-group xml:lang="en"><trans-title>Hepatitis E Virus SeroprevalencE among Different Age Groups of the Healthy Population of Kyrgyzstan</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лухверчик</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukhverchyk</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">lexx294@yandex.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алаторцева</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alatortseva</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">alatortseva@gmall.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нестеренко</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesterenko</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">lnnesterenko@pochta.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурматов</surname><given-names>А. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmatov</surname><given-names>A. Z.</given-names></name></name-alternatives><email xlink:type="simple">asilbeknurmat@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурматов</surname><given-names>З. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmatov</surname><given-names>Z. Sh.</given-names></name></name-alternatives><email xlink:type="simple">z.nurmatov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байызбекова</surname><given-names>Ж. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baiyzbekova</surname><given-names>Zh. A.</given-names></name></name-alternatives><email xlink:type="simple">djayna2001@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касымов</surname><given-names>О. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasymov</surname><given-names>O. T.</given-names></name></name-alternatives><email xlink:type="simple">npopm@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>M. I.</given-names></name></name-alternatives><email xlink:type="simple">michmich2@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зверев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zverev</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">vitalyzverev@outlook.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «НИИ вакцин и сывороток им. И.И. Мечникова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mechnikov Research Institute for Vaccines and Sera</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НПО «Профилактическая медицина» Минздрава Кыргызской Республики</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Production Association «Preventive Medicine»Ministry of Health of the Kyrgyz Republic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ «Институт полиомиелита и вирусных энцефалитов им. М.П. Чумакова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chumakov Institute of Poliomyelitis and Viral Encephalitides</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2016</year></pub-date><volume>15</volume><issue>1</issue><fpage>39</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лухверчик Л.Н., Алаторцева Г.И., Нестеренко Л.Н., Нурматов А.З., Нурматов З.Ш., Байызбекова Ж.А., Касымов О.Т., Михайлов М.И., Зверев В.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Лухверчик Л.Н., Алаторцева Г.И., Нестеренко Л.Н., Нурматов А.З., Нурматов З.Ш., Байызбекова Ж.А., Касымов О.Т., Михайлов М.И., Зверев В.В.</copyright-holder><copyright-holder xml:lang="en">Lukhverchyk L.N., Alatortseva G.I., Nesterenko L.N., Nurmatov A.Z., Nurmatov Z.S., Baiyzbekova Z.A., Kasymov O.T., Mikhailov M.I., Zverev V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/124">https://www.epidemvac.ru/jour/article/view/124</self-uri><abstract><p>Сведения о распространении серологических маркеров инфицирования вирусом гепатита Е среди населения эндемичных регионов являются важным индикатором для оценки эпидемиологической ситуации по этой инфекции. Настоящее исследование посвящено изучению частоты обнаружения антител класса G к вирусу гепатита Е (ВГЕ) у здорового населения различного возраста, проживающего в регионах Кыргызской Республики. С помощью набора реагентов «ДС-ИФА-АНТИ-HEV-G» (НПО «Диагностические системы», Россия) исследовано 648 образцов сывороток крови, полученных с декабря 2014 года по февраль 2015 года от лиц без патологии печени. IgG к вирусу гепатита Е были выявлены в 4,8% (n = 31) обследованных образцов. Проведен анализ данных по серопозитивности лиц различных возрастных групп, проживающих в разных регионах республики. Наибольшее количество серопозитивных лиц выявлено в г. Бишкеке и в Чуйской области. Наиболее часто антитела обнаруживались у лиц возрастных групп от 1 до 5 лет, от 15 до 19 лет и старше 50 лет. Полученные данные свидетельствуют о непрекращающейся циркуляции ВГЕ в межэпидемический период.</p></abstract><trans-abstract xml:lang="en"><p>Knowledge regarding distribution of serological markers of Hepatitis E Virus (HEV) infection in the population of endemic regions is an important indicator of the public health and hygiene. The aim of this study was to determine seroprevalence of HEV among different age groups of the population in Kyrgyzstan regions. 648 serum samples of persons without liver pathology received in December 2014 to February 2015 was tested by immunoassay kit «DS-EIA-ANTI-HEV-G» (Diagnostic systems, Russia). IgG antibodies to HEV were detected in 4.8% (n = 31) of the examined samples. An analysis of the level of seropositivity in different regions and in different age groups of the population was made. The greatest number of seropositive persons were identified in Bishkek and Chuskaya oblast. The antibodies were detected most frequently in individuals aged 1 to 5, 15 to 19 years old and older than 50 years old. The obtained data indicate the constant virus circulation in Kyrgyzstan in interepidemic period.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вирус гепатита Е</kwd><kwd>сероэпидемиология</kwd><kwd>hepatitis E virus</kwd><kwd>seroepidemiology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Labrique A. B., Zaman K., Hossain Z.et al. Population seroprevalence of hepatitis E virus antibodies in rural Bangladesh. The Am. J. of Trop. Med. and Hyg. 2009; 81 (5): 875 - 881.</mixed-citation><mixed-citation xml:lang="en">Labrique A. B., Zaman K., Hossain Z.et al. Population seroprevalence of hepatitis E virus antibodies in rural Bangladesh. The Am. J. of Trop. 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