epidemiologyЭпидемиология и ВакцинопрофилактикаEpidemiology and Vaccinal Prevention2073-30462619-0494«Numicom» LLC10.31631/2073-3046-2021-20-6-108-116epidemiology-1406Research ArticleОБЗОРREVIEWКлещевые возвратные лихорадки и геновидовое разнообразие боррелий: текущее состояние вопросаTick-Born Relapsing Fever and Genespecies Diversity of Borrelia: Current Statushttps://orcid.org/0000-0003-2532-0054ЧекановаТ. А.ChekanovaT. A.

Татьяна Александровна Чеканова – к. б. н., заведующая лабораторией эпидемиологии природно-очаговых инфекций

МоскваТел. +7 (903) 195-26-42

Tatiana A. Chekanova  – Cand. Sci. (Bio.), Head of Laboratory for Natural Focal Infection Epidemiology

MoscowTel. +7 (903) 195-26-42

tchekanova74@mail.ruhttps://orcid.org/0000-0002-1146-1430МанзенюкИ. Н.ManzeniukI. N.

Игорь Николаевич Манзенюк – к. м. н., помощник директора по научной работе

МоскваТел. +7 (926) 296-06-04

Igor N. Manzeniuk – Cand. Sci. (Med.), Aide to Director of Institute (Scientific work)

MoscowTel. +7 (926) 296-06-04

manzeniuk@cmd.suФБУН «Центральный научно-исследовательский институт эпидемиологии» РоспотребнадзораРоссияCentral Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-BeingRussian Federation202106012022206108116Copyright © Чеканова Т.А., Манзенюк И.Н., 20222022Чеканова Т.А., Манзенюк И.Н.Chekanova T.A., Manzeniuk I.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epidemvac.ru/jour/article/view/1406

Актуальность. Клещевые возвратные лихорадки, вызываемые патогенными для человека видами боррелий, недостаточно изучены. Цель обзора – оценка геновидового разнообразия боррелий с особым вниманием к группе возбудителей возвратных лихорадок и филогенетически смежных с ней видов, переносимых клещами. В обзоре также представлена актуальная информация об основных переносчиках (клещах) и их известном географическом распространении, природных резервуарах боррелий – возбудителей и потенциальных возбудителей клещевых возвратных лихорадок. Заключение. Новые виды боррелий, в т.ч. кандидатные, клады возвратных лихорадок и смежных филогенетических линий/групп, переносчиками которых являются не только аргасовые клещи, но и твердотельные иксодовые, заслуживают дальнейшего изучения. Сохранению эпидемического потенциала клещевых возвратных лихорадок могут способствовать климатические изменения, а также мало изученные адаптационные механизмы боррелий к вероятным переносчикам.

Relevance. Tick-borne relapsing fevers caused by Borrelia species pathogenic for humans are not well understood. Aim of this review is to assess the genetic diversity of Borrelia with special attention to the relapsing fever group and phylogenetically related species carried by ticks. The review also provides up-to-date information on the main vectors and their geographic distribution, reservoirs of borrelia – pathogens, and potential pathogens of tick-borne recurrent fevers. Conclusions. New types of Borrelia, including a candidate, of relapsing fever clade and related phylogenetic lines/groups, which are carried not only by argasid, but also by solid-body ixodids ticks, deserve further study. The preservation of the epidemic potential of tick-borne relapsing fever can be facilitated by climatic changes, and poorly studied adaptation mechanisms of Borrelia to the range of vectors.

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The authors declare that there are no conflicts of interest present.