<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2022-21-2-91-97</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-1527</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Вакцинация от COVID-19 пациентов с аллергическими заболеваниями. Позиция врача аллерголога-иммунолога. Обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Vaccination against COVID-19 Patients with Allergic Diseases. The Position of the Allergologist-Immunologist. Literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5846-851X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркелова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Markelova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Владимировна Маркелова – д. м. н., профессор, зав. кафедрой</p><p>г. Владивосток</p><p>+7 (914) 707-85-59</p></bio><bio xml:lang="en"><p>Elena V. Markelova – Dr. Sci. (Med.), Professor, Head department</p><p>Vladivostok</p></bio><email xlink:type="simple">markev2010@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4571-1749</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кныш</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Knysh</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Васильевич Кныш – к. м. н., доцент</p><p>Москва</p><p>+7 (995) 773-65-23</p></bio><bio xml:lang="en"><p>Sergey V. Knysh  – Cand. Sci. (Med.), Associate professor</p><p>Moscow</p></bio><email xlink:type="simple">immunolog.vl@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1382-9403</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костинов</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostinov</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Михаил Петрович Костинов – д. м. н., профессор, зав. лабораторией вакцинопрофилактики и иммунотерапии аллергических заболеваний;  зав. кафедрой </p><p>Москва</p><p>+7 (495) 917-52-64</p></bio><bio xml:lang="en"><p>Mikhail P. Kostinov – Dr. Sci. (Med.), Professor, Head of laboratory of vaccination and immunotherapy of allergic diseases;  Head of department</p><p>Moscow</p><p> </p></bio><email xlink:type="simple">monolit.96@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Тихоокеанский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific state medical university</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО Первый МГМУ им. И. М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО Первый МГМУ им. И. М. Сеченова Минздрава России (Сеченовский Университет); ФГБНУ «НИИ вакцин и сывороток им. И. И. Мечникова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mechnikov Research Institute of Vaccines and Sera</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>05</month><year>2022</year></pub-date><volume>21</volume><issue>2</issue><elocation-id>­91­-97</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Маркелова Е.В., Кныш С.В., Костинов М.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Маркелова Е.В., Кныш С.В., Костинов М.П.</copyright-holder><copyright-holder xml:lang="en">Markelova E.V., Knysh S.V., Kostinov M.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/1527">https://www.epidemvac.ru/jour/article/view/1527</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В настоящее время активно продолжается разработка вакцин против COVID-19, их клинические испытания, а также анализируется эффективность используемых вакцин. Очень важным вопросом станет то, как и когда вакцинировать пациентов с различными хроническими заболеваниями, что является относительными и абсолютными противопоказаниями для вакцинации, как различные заболевания могут сказаться на эффективности вакцинации.</p></sec><sec><title>Цель</title><p>Цель. Представить обзор наиболее значимых опубликованных материалов по вопросу вакцинации от COVID-19 пациентов с аллергическими заболеваниями, а также вероятности развития нежелательных явлений аллергической природы в ответ на введение вакцины. </p></sec><sec><title>Выводы</title><p>Выводы. Активное изучение вакцин, их эффективности и безопасности демонстрирует нам высокую надежность данных препаратов и отсутствие высоких, по сравнению с иными вакцинами, рисков развития нежелательных явлений. Анафилактические реакции на введение вакцин от COVID-19 встречаются не чаще, чем на любые другие вакцины, используемые в международной медицинской практике.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Currently, the development of vaccines against COVID-19, their clinical trials are actively continuing, and the effectiveness of the vaccines used is being analyzed. A very important issue will be how and when to vaccinate patients with various chronic diseases, what are the relative and absolute contraindications for vaccination, how various diseases can affect the effectiveness of vaccination.</p></sec><sec><title>Aims</title><p>Aims. To present an overview of the most significant published materials on the issue of vaccination against COVID19 patients with allergic diseases, as well as the likelihood of developing adverse events of an allergic nature in response to the introduction of the vaccine. </p></sec><sec><title>Conclusions</title><p>Conclusions. An active study of vaccines, their effectiveness and safety, demonstrates to us the high reliability of these drugs and the absence of high risks of adverse events in comparison with other vaccines. Anaphylactic reactions to the introduction of COVID-19 vaccines are not more common than for any other vaccines used in international medical practice.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вакцинация</kwd><kwd>COVID-19</kwd><kwd>аллергия</kwd><kwd>нежелательные явления</kwd><kwd>астма</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vaccination</kwd><kwd>COVID-19</kwd><kwd>allergy</kwd><kwd>adverse events</kwd><kwd>asthma</kwd><kwd>review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Weakly Operational Update on COVID-19. WHO. 2022. I. 93. Доступно на: https://www.who.int/publications/m/item/weekly-operational-update-on-covid19---1-march-2022. Ссылка активна на 21 апреля</mixed-citation><mixed-citation xml:lang="en">Weakly Operational Update on COVID-19. WHO. 2022. I. 93. Available at: https://www.who.int/publications/m/item/weekly-operational-update-on-covid19---1-march-2022. Accessed: 21 Apr 2022</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dierick BJH, van der Molen T, Flokstra-de Blok BMJ, et al. Burden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy. Expert Rev Pharmacoecon Outcomes Res. 2020;20(5):437–453. doi:10.1080/14737167.2020.1819793</mixed-citation><mixed-citation xml:lang="en">Dierick BJH, van der Molen T, Flokstra-de Blok BMJ, et al. Burden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy. Expert Rev Pharmacoecon Outcomes Res. 2020;20(5):437–453. doi:10.1080/14737167.2020.1819793</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. World Allergy Organ J. 2014;7(1):12. doi:10.1186/1939-4551-7-12</mixed-citation><mixed-citation xml:lang="en">Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. World Allergy Organ J. 2014;7(1):12. doi:10.1186/1939-4551-7-12</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898–900. doi:10.1016/j.ymthe.2021.01.030</mixed-citation><mixed-citation xml:lang="en">Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898–900. doi:10.1016/j.ymthe.2021.01.030</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dages KN, Pitlick MM, Joshi AY, Park MA. Risk of allergic reaction in patients with atopic disease and recent coronavirus disease 2019 vaccination. Ann Allergy Asthma Immunol. 2021;127(2):257–258. doi:10.1016/j.anai.2021.04.024</mixed-citation><mixed-citation xml:lang="en">Dages KN, Pitlick MM, Joshi AY, Park MA. Risk of allergic reaction in patients with atopic disease and recent coronavirus disease 2019 vaccination. Ann Allergy Asthma Immunol. 2021;127(2):257–258. doi:10.1016/j.anai.2021.04.024</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Turner PJ, Ansotegui IJ, Campbell DE, et al. COVID-19 vaccine-associated anaphylaxis: A statement of the World Allergy Organization Anaphylaxis Committee. World Allergy Organ J. 2021;14(2):100517. doi:10.1016/j.waojou.2021.100517</mixed-citation><mixed-citation xml:lang="en">Turner PJ, Ansotegui IJ, Campbell DE, et al. COVID-19 vaccine-associated anaphylaxis: A statement of the World Allergy Organization Anaphylaxis Committee. World Allergy Organ J. 2021;14(2):100517. doi:10.1016/j.waojou.2021.100517</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Banerji A, Wolfson AR, Wickner PG, Robnison LB, et al. COVID-19 Vaccination in Patients with Reported Allergic Reactions: Updated Evidence and Suggested Approach. // The Journal of Allergy and Clinical Immunology: In Practice. 2021. Vol. 9. I.6. P. 2135–2138. https://doi.org/10.1016/j.jaip.2021.03.053</mixed-citation><mixed-citation xml:lang="en">Banerji A, Wolfson AR, Wickner PG, Robnison LB, et al. COVID-19 Vaccination in Patients with Reported Allergic Reactions: Updated Evidence and Suggested Approach. The Journal of Allergy and Clinical Immunology: In Practice. 2021. Vol. 9. I.6. P. 2135–2138. https://doi.org/10.1016/j.jaip.2021.03.053</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Nilsson L, Csuth Á, Storsaeter J, Garvey LH, Jenmalm MC. Vaccine allergy: evidence to consider for COVID-19 vaccines. Curr Opin Allergy Clin Immunol. 2021;21(4):401–409. doi:10.1097/ACI.0000000000000762</mixed-citation><mixed-citation xml:lang="en">Nilsson L, Csuth Á, Storsaeter J, Garvey LH, Jenmalm MC. Vaccine allergy: evidence to consider for COVID-19 vaccines. Curr Opin Allergy Clin Immunol. 2021;21(4):401–409. doi:10.1097/ACI.0000000000000762</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Erdeljic Turk V. Anaphylaxis associated with the mRNA COVID-19 vaccines: Approach to allergy investigation. Clin Immunol. 2021;227:108748. doi:10.1016/j.clim.2021.108748</mixed-citation><mixed-citation xml:lang="en">Erdeljic Turk V. Anaphylaxis associated with the mRNA COVID-19 vaccines: Approach to allergy investigation. Clin Immunol. 2021;227:108748. doi:10.1016/j.clim.2021.108748</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Klimek L, Novak N, Cabanillas B, et al. Allergenic components of the mRNA-1273 vaccine for COVID-19: Possible involvement of polyethylene glycol and IgG-mediated complement activation. Allergy. 2021;76(11):3307–3313. doi:10.1111/all.14794</mixed-citation><mixed-citation xml:lang="en">Klimek L, Novak N, Cabanillas B, et al. Allergenic components of the mRNA-1273 vaccine for COVID-19: Possible involvement of polyethylene glycol and IgG-mediated complement activation. Allergy. 2021;76(11):3307–3313. doi:10.1111/all.14794</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Park HJ, Montgomery JR, Boggs NA. Anaphylaxis After the Covid-19 Vaccine in a Patient With Cholinergic Urticaria [published online ahead of print, 2021 Apr 14]. Mil Med. 2021;usab138. doi:10.1093/milmed/usab138</mixed-citation><mixed-citation xml:lang="en">Park HJ, Montgomery JR, Boggs NA. Anaphylaxis After the Covid-19 Vaccine in a Patient With Cholinergic Urticaria [published online ahead of print, 2021 Apr 14]. Mil Med. 2021;usab138. doi:10.1093/milmed/usab138</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kadali RAK, Janagama R, Peruru S, et al. Non-life-threatening adverse effects with COVID-19 mRNA-1273 vaccine: A randomized, cross-sectional study on healthcare workers with detailed self-reported symptoms. J Med Virol. 2021;93(7):4420–4429. doi:10.1002/jmv.26996</mixed-citation><mixed-citation xml:lang="en">Kadali RAK, Janagama R, Peruru S, et al. Non-life-threatening adverse effects with COVID-19 mRNA-1273 vaccine: A randomized, cross-sectional study on healthcare workers with detailed self-reported symptoms. J Med Virol. 2021;93(7):4420–4429. doi:10.1002/jmv.26996</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Shavit R, Maoz-Segal R, Iancovici-Kidon M, et al. Prevalence of Allergic Reactions After Pfizer-BioNTech COVID-19 Vaccination Among Adults With High Allergy Risk. JAMA Netw Open. 2021;4(8):e2122255. doi:10.1001/jamanetworkopen.2021.22255</mixed-citation><mixed-citation xml:lang="en">Shavit R, Maoz-Segal R, Iancovici-Kidon M, et al. Prevalence of Allergic Reactions After Pfizer-BioNTech COVID-19 Vaccination Among Adults With High Allergy Risk. JAMA Netw Open. 2021;4(8):e2122255. doi:10.1001/jamanetworkopen.2021.22255</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Wolfson AR, Robinson LB, Li L, et al. First-Dose mRNA COVID-19 Vaccine Allergic Reactions: Limited Role for Excipient Skin Testing. J Allergy Clin Immunol Pract. 2021;9(9):3308–3320.e3. doi:10.1016/j.jaip.2021.06.010</mixed-citation><mixed-citation xml:lang="en">Wolfson AR, Robinson LB, Li L, et al. First-Dose mRNA COVID-19 Vaccine Allergic Reactions: Limited Role for Excipient Skin Testing. J Allergy Clin Immunol Pract. 2021;9(9):3308–3320.e3. doi:10.1016/j.jaip.2021.06.010</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Pfaar O, Klimek L, Hamelmann E, et al. COVID-19 vaccination of patients with allergies and type-2 inflammation with concurrent antibody therapy (biologicals) - A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI) and the German Society for Applied Allergology (AeDA). Allergol Select. 2021;5:140–147. doi:10.5414/ALX02241E</mixed-citation><mixed-citation xml:lang="en">Pfaar O, Klimek L, Hamelmann E, et al. COVID-19 vaccination of patients with allergies and type-2 inflammation with concurrent antibody therapy (biologicals) - A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI) and the German Society for Applied Allergology (AeDA). Allergol Select. 2021;5:140–147. doi:10.5414/ALX02241E</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Магаршак О. О., Костинов М. П. Проблемы вакцинации детей с аллергическими заболеваниями. Лечащий врач. 2008. № 9. С. 44–48.</mixed-citation><mixed-citation xml:lang="en">Magarshak OO, Kostinov MP. Problemy vakcinacii detej s allergicheskimi zabolevanijami. Lechashhij vrach. 2008;9:44–48 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ильина Н. И., Курбачева О. М., Латышева Е. А. и др. Вакцинация пациентов с аллергическими заболеваниями против новой коронавирусной инфекции COVID-19: позиционный документ Российской ассоциации аллергологов и клинических иммунологов. Российский аллергологический журнал. - 2021. - Т. 18. - №3. - C. 93–97. doi: 10.36691/RJA1479</mixed-citation><mixed-citation xml:lang="en">Ilyina NI, Kurbacheva OM, Latysheva EA, Latysheva TV, et al. Vaccination of patients with allergic disease against novel coronavirus infection: position paper of the Russian Association of Allergology and Clinical Immunology. Russian Journal of Allergy. 2021;18(3):93–97(In Russ.). doi: 10.36691/RJA1479</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Костинов М. П. Вакцинация взрослых – от стратегии к тактике. Руководство для врачей. М.: МДВ, 2020.</mixed-citation><mixed-citation xml:lang="en">Kostinov MP, Adult vaccination – from strategy to tactics. A guide for doctors. M: MDV, 2020 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Костинов М.П., Гервазиева В.Б., Балаболкин И.И., Максимова Н.М., Переверзева Н.В. Вакцинопрофилактика дифтерии и столбняка у детей, страдающих бронхиальной астмой и астматическим бронхитом. Журнал микробиологии, эпидемиологии и иммунобиологии. 1993;(3):76–80.</mixed-citation><mixed-citation xml:lang="en">Kostinov MP, Gervazieva VB, Balabolkin II, Maksimova NM, et al. Vaktsinoprofilaktika difterii i stolbniaka u deteĭ, stradaiushchikh bronkhial’noĭ astmoĭ i astmaticheskim bronkhitom [The vaccinal prevention of diphtheria and tetanus in children suffering from bronchial asthma and asthmatic bronchitis]. Zhurnal mikrobiologii, epidemiologii i immunobiologii 1993;(3):76–80 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Thyssen JP, Vestergaard C, Barbarot S, et al. European Task Force on Atopic Dermatitis: position on vaccination of adult patients with atopic dermatitis against COVID-19 (SARS-CoV-2) being treated with systemic medication and biologics. J Eur Acad Dermatol Venereol. 2021;35(5):e308–e311. doi:10.1111/jdv.17167</mixed-citation><mixed-citation xml:lang="en">Thyssen JP, Vestergaard C, Barbarot S, et al. European Task Force on Atopic Dermatitis: position on vaccination of adult patients with atopic dermatitis against COVID-19 (SARS-CoV-2) being treated with systemic medication and biologics. J Eur Acad Dermatol Venereol. 2021;35(5):e308–e311. doi:10.1111/jdv.17167</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nittner-Marszalska M, Rosiek-Biegus M, Kopeć A, et al. Pfizer-BioNTech COVID-19 Vaccine Tolerance in Allergic versus Non-Allergic Individuals. Vaccines (Basel). 2021;9(6):553. Published 2021 May 25. doi:10.3390/vaccines9060553</mixed-citation><mixed-citation xml:lang="en">Nittner-Marszalska M, Rosiek-Biegus M, Kopeć A, et al. Pfizer-BioNTech COVID-19 Vaccine Tolerance in Allergic versus Non-Allergic Individuals. Vaccines (Basel). 2021;9(6):553. Published 2021 May 25. doi:10.3390/vaccines9060553</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Johnston MS, Galan A, Watsky KL, Little AJ. Delayed Localized Hypersensitivity Reactions to the Moderna COVID-19 Vaccine: A Case Series. JAMA Dermatol. 2021;157(6):716–720. doi:10.1001/jamadermatol.2021.1214</mixed-citation><mixed-citation xml:lang="en">Johnston MS, Galan A, Watsky KL, Little AJ. Delayed Localized Hypersensitivity Reactions to the Moderna COVID-19 Vaccine: A Case Series. JAMA Dermatol. 2021;157(6):716–720. doi:10.1001/jamadermatol.2021.1214</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Rasmussen, TH, Mortz, CG, Georgsen, TK, Rasmussen, HM, Kjaer, HF, Bindslev-Jensen, C. Patients with suspected allergic reactions to COVID-19 vaccines can be safely revaccinated after diagnostic work-up. Clin Transl Allergy. 2021;e12044. https://doi.org/10.1002/clt2.12044</mixed-citation><mixed-citation xml:lang="en">Rasmussen, TH, Mortz, CG, Georgsen, TK, Rasmussen, HM, Kjaer, HF, Bindslev-Jensen, C. Patients with suspected allergic reactions to COVID-19 vaccines can be safely revaccinated after diagnostic work-up. Clin Transl Allergy. 2021;e12044. https://doi.org/10.1002/clt2.12044</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Greenhawt M, Abrams EM, Shaker M, et al. The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. // J Allergy Clin Immunol Pract. 2021;9(10):3546–3567. doi:10.1016/j.jaip.2021.06.006</mixed-citation><mixed-citation xml:lang="en">23. Greenhawt M, Abrams EM, Shaker M, et al. The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. J Allergy Clin Immunol Pract. 2021;9(10):3546–3567. doi:10.1016/j.jaip.2021.06.006</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
