epidemiologyЭпидемиология и ВакцинопрофилактикаEpidemiology and Vaccinal Prevention2073-30462619-0494«Numicom» LLC10.31631/2073-3046-2016-15-3-66-71epidemiology-167Research ArticleВАКЦИНОПРОФИЛАКТИКАVACCINAL PREVENTIONПроблемы вакцинопрофилактики глубоких микозовPROBLEMS OF VACCINAL PREVENTION OF DEEP MYCOSESЛипницкийА. В.LipnitskyA. V.microgrib.lab@yandex.ruПоловецН. В.PoloveteN. V.noemail@neicon.ruАнтоновВ. А.AntonovV. A.noemail@neicon.ruФКУЗ «Волгоградский научно-исследовательский противочумный институт» РоспотребнадзораРоссияFederal State Health Agency «Volgograd Research Institute for Plaque Control» of Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingRussian Federation2016200620161536671Copyright © Липницкий А.В., Половец Н.В., Антонов В.А., 20162016Липницкий А.В., Половец Н.В., Антонов В.А.Lipnitsky A.V., Polovete N.V., Antonov V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epidemvac.ru/jour/article/view/167

В обзоре литературы представлены данные последних лет относительно стратегии получения и протективных свойств различных экспериментальных вакцин против оппортунистических и особо опасных глубоких микозов. Обсуждается роль Т-лимфоцитов Th1 и Th17 типов, взаимосвязи CD4+T- и СВ8+Т-клеток в иммунном ответе и сохранении иммунологической памяти после введения противогрибковой вакцины.

A literature review presents date obtained during the last years about the strategy of production and protective characteristics of different experimental vaccines against opportunistic and particularly dangerous deep mycoses. The role of T-lymphocytes of Th1 and Th17 types, interactions of CD4+T - and CD8+T-cells in the immune response and maintenance of immunologic memory after immunization with vaccines against mycoses are discussed.

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The authors declare that there are no conflicts of interest present.