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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2023-22-2-107-116</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-1786</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Инфекционная заболеваемость в закрытых учреждениях долговременного ухода в «доковидный период»</article-title><trans-title-group xml:lang="en"><trans-title>Infectious Morbidity in Closed Long-Term Care Facilities in the «Pre-COVID Stage»</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4228-9044</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акимкин</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Akimkin</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василий Геннадьевич Акимкин – академик РАН, доктор медицинских наук, профессор, директор.</p><p>Москва, +7  (903) 013-09-74</p></bio><bio xml:lang="en"><p>Vasily G. Akimkin – Academician of the Russian Academy of Sciences, Dr. Sci. (Med.), Professor, Director.</p><p>Moscow, +7 (903) 013-09-74</p></bio><email xlink:type="simple">vgakimkin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4429-9844</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давидова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydova</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Георгиевна Давидова – аспирант ЦНИИЭ; врачэпидемиолог Филиала ФБУЗ «Центр гигиены и эпидемиологии в городе Москве» в Восточном административном округе города Москвы.</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalia G. Davidova – post-graduate student of CRIERr; epidemiologist of the Branch of the FBUZ «Center for Hygiene and Epidemiology in the City of Moscow» in the Eastern Administrative District of Moscow</p></bio><email xlink:type="simple">dawidowa.nat2016@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1322-0155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Углева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ugleva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Викторовна Углева – доктор медицинских наук, доцент, консультант организационно-методического отдела административно-управленческого подразделения.</p><p>111123, Москва, Новогиреевская ул., д. 3а. +7 (495) 672-10-69</p></bio><bio xml:lang="en"><p>Svetlana V. Ugleva – Dr. Sci. (Med.), Assoc. Prof., consultant, Organizational and methodological department.</p><p>3а, Novogireevskaya str., Moscow, 111123, +7 (495) 672-10-69</p></bio><email xlink:type="simple">uglevas@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6539-4878</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Понежева</surname><given-names>Ж. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponezheva</surname><given-names>Zh. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жанна Бетовна Понежева – доктор медицинских наук, заведующая клиническим отделом инфекционной патологии.</p><p>Москва, +7 (903) 145-50-07</p></bio><bio xml:lang="en"><p>Zhanna B. Ponezheva – Dr. Sci. (Med.), Head of the Clinical Department.</p><p>Moscow, +7 (903) 145-50-07</p></bio><email xlink:type="simple">doktorim@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7102-5414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабалина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabalina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Васильевна Шабалина – доктор медицинских наук, профессор, ведущий научный сотрудник.</p><p>Москва, +7 (906) 743-48-64</p></bio><bio xml:lang="en"><p>Svetlana V. Shabalina – Dr. Sci. (Med.), Professor.</p><p>Moscow, +7 (906) 743-48-64</p></bio><email xlink:type="simple">svs2810@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «ЦНИИ Эпидемиологии» Роспотребнадзора</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «ЦНИИ Эпидемиологии» Роспотребнадзора; Филиал ФБУЗ «Центр гигиены и эпидемиологии в городе Москве» в ВАО</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Branch of the Federal State Budgetary Institution "Center of Hygiene and Epidemiology in the city of Moscow" in the ЕАО of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>05</month><year>2023</year></pub-date><volume>22</volume><issue>2</issue><fpage>107</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акимкин В.Г., Давидова Н.Г., Углева С.В., Понежева Ж.Б., Шабалина С.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Акимкин В.Г., Давидова Н.Г., Углева С.В., Понежева Ж.Б., Шабалина С.В.</copyright-holder><copyright-holder xml:lang="en">Akimkin V.G., Davydova N.G., Ugleva S.V., Ponezheva Z.B., Shabalina S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/1786">https://www.epidemvac.ru/jour/article/view/1786</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Люди пожилого возраста стали самым быстрорастущим сегментом мирового населения за последние несколько десятилетий. Количество лиц старше трудоспособного возраста в России, а вместе с ними и граждан, находящихся в закрытых учреждениях длительного ухода (ЗУДУ), растёт. Проживающие в ЗУДУ относятся к группе риска по заболеваемости, а сами эти учреждения представляют среду для распространения инфекций.</p></sec><sec><title>Цель</title><p>Цель. Провести по данным научных публикаций анализ инфекционной заболеваемости пациентов ЗУДУ в «доковидный период». Осуществлён научный обзор исследований на русском и английском языках с использованием информационных порталов и платформ eLIBRARY.ru, Web of Science, PubMed, Google академия и Scopus за период 1981–2022 гг. Поиск осуществлялся по ключевым словам. Информация о наиболее частых инфекционных заболеваниях, поражающих жителей закрытых учреждений долговременного ухода, являлась критерием включения в выборку публикаций. Из 16171 первоначально выявленной статьи после первичного анализа была отобрана 61 публикация.</p></sec><sec><title>Заключение</title><p>Заключение. Ведущими инфекционными заболеваниями в ЗУДУ, по разным оценкам, являются: острые респираторные инфекции, пневмонии, инфекции мочевыводящих путей, кожи и слизистых, острые кишечные инфекции. Исследования, проводимые в различных ЗУДУ в странах Европы, России, США, Азии, говорят о большой распространённости инфекционных заболеваний, высокой колонизации резидентов устойчивыми к противомикробным препаратам патогенами, а также о вероятности выноса инфекции за пределы ЗУДУ в другие учреждения долговременного ухода и лечебно-профилактические организации.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Elderly people have become the fastest growing segment of the global population over the past few decades. The number of people over the working age in Russia, and with them citizens living in closed long-term care facilities (CLTFS), is growing. Residents of these organizations belong to the risk group, and CLTFS have a number of characteristics that turn these institutions into a unique environment for the spread of infectious diseases.</p></sec><sec><title>Aims</title><p>Aims. To analyze the CLTFS residents infectious morbidity in the "pre-covid stage" (according to literature sources). A scientific review of research in Russian and English using information portals and platforms has been carried out eLIBRARY. ru , Web of Science, PubMed, Google Academy and Scopus for the period 1981-2022. The search was carried out by keywords. Information about the most frequent infectious diseases affecting residents of closed long-term care institutions was the criterion for inclusion in the sample of publications. Out of 16171 initially identified articles, 61 publications were selected after initial analysis.</p></sec><sec><title>Conclusions</title><p>Conclusions. According to various estimates, the leading infectious diseases in CLTFS were: acute respiratory infections, pneumonia, urinary tract infections, skin and mucous infections, acute intestinal infections. The article describes pathogens and their prevalence in CLTFS including pathogens with multiple drug resistance (MDR), describes the resistance of bacteria to antimicrobial drugs formation problem in these organizations, as well as development of certain diseases risk factors. Studies conducted in various CLTFS in Europe, Russia, the USA, and Asia indicate a high prevalence of infectious diseases among their residents, high colonization of residents with antimicrobial-resistant pathogens, as well as the infection transmission probability from the CLTFS and its spread to other long-term care institutions and medical and preventive organizations.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>закрытые учреждения долговременного ухода</kwd><kwd>дома престарелых</kwd><kwd>пневмонии</kwd><kwd>инфекции мочевыводящих путей</kwd><kwd>инфекции кожи</kwd><kwd>резистентность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>closed long-term care facilities</kwd><kwd>nursing homes</kwd><kwd>pneumonia</kwd><kwd>urinary tract infections</kwd><kwd>skin infections</kwd><kwd>resistance No conflict of interest to declare</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aina, F. 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