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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2016-15-5-30-37</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-355</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY</subject></subj-group></article-categories><title-group><article-title>Эпидемиологические особенности пандемического гриппа в Кыргызстане, обусловленного вирусом гриппа А (H1N1)pdm</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касымбекова</surname><given-names>К. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasymbekova</surname><given-names>K. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурматов</surname><given-names>З. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmatov</surname><given-names>Z. S.</given-names></name></name-alternatives><email xlink:type="simple">z.nurmatov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комиссаров</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Komissarov</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Переяслов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pereyaslov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpova</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сапарова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Saparova</surname><given-names>G. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кыргызский государственный медицинский институт переподготовки и повышения квалификации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kyrgyzsky State Medical Institute of retraining and advanced training</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НИИ гриппа» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Federal State Budgetary Institution «Research Influenza Institute» of Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Европейское Бюро Всемирной Организации Здравоохранения</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Evropeyskoe Bureau of the World Health Organization</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Департамент профилактики заболеваний и госсанэпиднадзора Минздрава Кыргызской Республики</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Departament disease prevention and Sanitary Inspection Ministry of Health The Kyrgyz Republic</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2016</year></pub-date><volume>15</volume><issue>5</issue><fpage>30</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Касымбекова К.Т., Нурматов З.Ш., Комиссаров А.Б., Фадеев А.В., Переяслов Д.В., Карпова Л.С., Сапарова Г.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Касымбекова К.Т., Нурматов З.Ш., Комиссаров А.Б., Фадеев А.В., Переяслов Д.В., Карпова Л.С., Сапарова Г.Н.</copyright-holder><copyright-holder xml:lang="en">Kasymbekova K.T., Nurmatov Z.S., Komissarov A.B., Fadeev A.V., Pereyaslov D.V., Karpova L.S., Saparova G.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/355">https://www.epidemvac.ru/jour/article/view/355</self-uri><abstract><p>На основании многолетнего ретроспективного анализа заболеваемости гриппом и ОРВИ, а также данных дозорного эпидемиологического надзора изучены особенности пандемического гриппа А(H1N1)рdm09 в Кыргызстане. Проведена сравнительная молекулярно-генетическая характеристика вирусов гриппа А(H1N1)pdm09, выделенных в Кыргызстане, с референс-штаммами, рекомендованными Всемирной организацией здравоохранения (ВОЗ) для включения в состав противогриппозной вакцины.</p></abstract><trans-abstract xml:lang="en"><p>Relevance. Virological laboratory of the Department of prevention of diseases and Sanitary Inspection Healthcare Ministry f of the Kyrgyz Republic is nominated as the National Centre for Influenza Surveillance and accreditated by WHO, and in 2009 is included into a global network of influenza Goal. The purpose of this study - Assessment of epidemic features of manifestations of pandemic influenza A (H1N1) pdm09 in 2009 on the territory of the Kyrgyz Republic, as a comparative study of the molecular and genetic characteristics of influenza A virus (H1N1) pdm09, circulating on the territory of the Republic and the influenza virus reference strains recommended WHO for inclusion in the vaccine for the northern hemisphere. Materials and methods. On the basis of long-term retrospective analysis of the incidence of influenza and severe acute respiratory infections (SARI), and sentinel epidemiological surveillance (SS) data studied pandemic especially in Kyrgyzstan due to influenza A(H1N1)pdm09. Comparative molecular genetic characteristics of influenza viruses A(H1N1)pdm09 allocated in Kyrgyzstan, with reference strains recommended by the World Health Organization (WHO) for inclusion in the vaccine. Results. Overall, the analysis of the results of laboratory tests carried out as part of the routine and sentinel surveillance showed that from January 2009 to March 2010 at 38.8% of those surveyed from among, influenza viruses (at 655 out of 1687) were found. From January to April 2009 in the main circulating influenza A virus (H3N2), which accounted for 55.9 - 77.9% of the number of positive findings. Seasonal influenza A virus (H1N1) was detected in January - February (35.3 and 13.4%, respectively). The share of the flu virus in January accounted for 8%, in March-April - 25%. Not typeable influenza A virus was detected in February in 8.7% of cases. Conclusions. The results of the molecular genetic and virological studies have shown that the influenza pandemic in 2009 in the Republic was due to the spread of pandemic influenza virus A (H1N1) pdm09.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Кыргызстан</kwd><kwd>молекулярно-генетическая характеристика вирусов гриппа А(H1N1)pdm09</kwd><kwd>референс штаммы</kwd><kwd>пандемический грипп</kwd><kwd>Kyrgyzstan</kwd><kwd>molecular genetic characteristics of influenza viruses A(H1N1)pdm09</kwd><kwd>reference strains of pandemic influenza</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Нурматов З.Ш. Эпидемиологические особенности пандемического гриппа A(H1N1)2009 в Кыргызской Республике. Бишкек. Здравоохранение Кыргызстана. 2010; 4: 129 - 132.</mixed-citation><mixed-citation xml:lang="en">Nurmatov Z.Sh. 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