epidemiologyЭпидемиология и ВакцинопрофилактикаEpidemiology and Vaccinal Prevention2073-30462619-0494«Numicom» LLC10.31631/2073-3046-2018-17-1-40-47epidemiology-399Research ArticleОРИГИНАЛЬНАЯ СТАТЬЯORIGINAL ARTICLESАнализ смертности пациентов с ВИЧ-инфекцией на примере региона с высокой распространенностью инфекцииAnalysis Mortality in Patients with HIV-infection on Example of a Region with a High Prevalence of InfectionРозенбергВ. Я.RosenbergV. Ya.rovlad@inbox.ruПлотниковаЮ. К.PlotnikovaYu. K.ВоронинЕ. Е.VoroninE. E.ФКУ «Республиканская клиническая инфекционная больница»РоссияFederal Governmental Institution «Republican Clinical Infectious Diseases Hospital»Russian FederationГБУЗ «Иркутский областной центр по профилактике и борьбе со СПИД и инфекционными заболеваниями»РоссияState Budgetary Institution of Public Health «Irkutsk Regional Center for the Prevention and Control of AIDS and Infectious Diseases»Russian Federation2018200220181714047Copyright © Розенберг В.Я., Плотникова Ю.К., Воронин Е.Е., 20182018Розенберг В.Я., Плотникова Ю.К., Воронин Е.Е.Rosenberg V.Y., Plotnikova Y.K., Voronin E.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epidemvac.ru/jour/article/view/399

Смертность от СПИДа является ключевым индикатором эффективности противодействия эпидемии ВИЧ-инфекции. На примере Иркутской области как региона с высокой поражённостью ВИЧ проведен анализ основных показателей и причин смертности пациентов с ВИЧ-инфекцией. Показана ключевая роль патологии дыхательной системы (туберкулез, пневмонии) в структуре смертности, а также четкое положительное влияние антиретровирусной терапии на развитие СПИДа и выживаемость пациентов с ВИЧ-инфекцией. 

Relevance The HIV epidemic, registered worldwide since the early 1980s, is currently continuing its development in most countries, and, according to the Joint United Nations Program on HIV/AIDS (UNAIDS, 2016), covers more than 36 million people (including 1.8 million children) AIDS mortality is a key indicator of the effectiveness of the response to the HIV epidemic. On the example of the Irkutsk region as a region with high lesion, an analysis of the main indicators and causes of death of patients with HIV infection was carried out.

Goal – analysis of the mortality of HIV / AIDS patients by the example of a region with a high degree of defeat in order to determine the key criteria for evaluating activities to reduce the mortality from HIV/AIDS.

Materials and methods An analysis was made of the causes of mortality of patients with HIV infection in the Irkutsk region in 2014– 2016, using comparative data of modern domestic and foreign literature (including total mortality), as well as accounting and reporting documentation of the Irkutsk Regional Center for prevention and control of AIDS and infectious diseases.

Results 1

Results 1. There is an increase in the death rate of HIV-infected people, including those caused by HIV. 2. The increase in mortality practically does not lead to an increase in mortality due to a parallel increase in the number of people living with HIV. 3. The main causes of death from HIV infection (AIDS) are pathologies with primary respiratory system damage: tuberculosis and pneumonia, which requires special attention in developing approaches to diagnosis, recording, treatment and prevention of these diseases, as well as assessing the impact of vaccination of patients with HIV infection against pneumococcus on mortality from pneumonia. 4. The increase in ART coverage of all patient populations contributes to the stabilization of mortality from HIV/AIDS.

Conclusions

Conclusions: the most important for assessing the impact of ongoing efforts of the health system to reduce mortality among HIVinfected patients is the correct registration and diagnosis (including posthumous) of AIDS-indicative diseases, certainly associated with the progression of HIV infection. 

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The authors declare that there are no conflicts of interest present.