epidemiologyЭпидемиология и ВакцинопрофилактикаEpidemiology and Vaccinal Prevention2073-30462619-0494«Numicom» LLCepidemiology-562Research ArticleКОНФЕРЕНЦИИCONFERENCEАктуальность четырехвалентных гриппозных вакцин. Мировой опытThe Relevance of Tetravalent Influenza Vaccines. World experienceОстерхаусА. Д. М. Е.OsterhausA. D. M. E.

Албертус Доминикус Марцеллинус Ерасмус (AB) Остерхаус – профессор, доктор, директор

Ганновер

Albertus Dominicus Marcellinus Erasmus (AB) Osterhaus – Prof. dr., directeur

Hannover

Научно-исследовательский центр опасных и зоонозных инфекцийГерманияResearch Center for Dangerous and Zoonotic InfectionsGermany2018180920181747683Copyright © Остерхаус А.М., 20182018Остерхаус А.М.Osterhaus A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epidemvac.ru/jour/article/view/562

Дан обзор вирусологии гриппа, и особенностей истории эволюции возбудителя. Приведены данные международного многолетнего мониторинга и результаты собственных исследований, свидетельствующие о высоком пандемическом потенциале вируса в связи с его способностью постоянно меняться. На примерах анализа незначительных, но постоянных изменений сезонных вирусов гриппа рассмотрены потенциальные угрозы. На основании накопленного опыта и расчетов, полученных в математических моделях, дается оценка вакцинации как наиболее эффективного превентивного мероприятия и обоснование актуальности применения четырехвалентных вакцин против гриппа, особенно у молодых людей.

An overview of influenza virology, epidemiology and evolution history peculiarities is given. Data from international influenza survey and own study results are presented demonstrating influenza virus high pandemic potency due to its ability to change constantly. Using the examples of seasonal influenza minor but constant changes, virtual pandemic hazard is discussed. Based on the international surveillance data and using mathematical model findings, vaccination is considered to be most effective preventive measure, and justification for quadrivalent influenza vaccine apply, especially in young persons is presented.

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The authors declare that there are no conflicts of interest present.