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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">epidemiology-567</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОНФЕРЕНЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CONFERENCE</subject></subj-group></article-categories><title-group><article-title>100 лет пандемии: уроки истории. Новый этап вакцинопрофилактики</article-title><trans-title-group xml:lang="en"><trans-title>100 Years after the Spanish Flu Pandemic. The Evolution of the Influenza Virus and the Development of the Flu Vaccine</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брико</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Briko</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Брико Николай Иванович – академик РАН, доктор медицинских наук, профессор. Заслуженный деятель науки Российской Федерации, заведующий кафедрой эпидемиологии и доказательной медицины Сеченовского университета</p><p> </p></bio><bio xml:lang="en"><p>Nikolay I. Briko – academic of the Russian Academyof Sciences, Dr. Sci. (Med.), professor, head of the department of epidemiology and evidencebased medicine at Sechenov University</p><p>Moscow</p></bio><email xlink:type="simple">briko@mma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский ГМУ им. И. М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>18</day><month>09</month><year>2018</year></pub-date><volume>17</volume><issue>4</issue><fpage>68</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Брико Н.И., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Брико Н.И.</copyright-holder><copyright-holder xml:lang="en">Briko N.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/567">https://www.epidemvac.ru/jour/article/view/567</self-uri><abstract><p>В сообщении развернута историческая панорама эпидемий и пандемий гриппа от Гиппократа до наших дней. Дан углубленный анализ пандемий и эпидемий ХХ и ХХI веков. Представлена характеристика вируса гриппа, его эпидемиология и система надзора за инфекцией. В историческом, научном и практическом аспектах рассмотрена актуальность специфической профилактики гриппа.</p></abstract><trans-abstract xml:lang="en"><p>The report includes a historical panorama of flu epidemics and pandemic from Hippocrates to the present day. An in-depth analysis of the pandemics and epidemics of the 20th and 21st centuries is given. The characteristics of the influenza virus, its epidemiology and the system of infection surveillance are presented. In the historical, scientific and practical aspects, relevancy for specific prevention of influenza has been considered.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>грипп</kwd><kwd>эпидемия</kwd><kwd>пандемия</kwd><kwd>вакцина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>influenza</kwd><kwd>epidemic</kwd><kwd>pandemic</kwd><kwd>vaccine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chronicle of Influenza Pandemics, CW Potter. In: Textbook of Influenza. Eds.: Nicholson, Webster &amp; Hay. Blackwell Science, Oxford, 1998: 3–19.</mixed-citation><mixed-citation xml:lang="en">Chronicle of Influenza Pandemics, CW Potter. In: Textbook of Influenza. Eds.: Nicholson, Webster &amp; Hay. 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