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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2018-17-5-38-44</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-575</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОНФЕРЕНЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CONFERENCE</subject></subj-group></article-categories><title-group><article-title>Эпидемиологические проявления и оценка риска развития меланомы и других злокачественных новообразований кожи в Алтайском крае</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological Manifestations and Risk Assessment of Melanoma and other Skin Cancers in Altaiskiy Krai</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0756-2271</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блох</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Blokh</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Игоревич Блох – аспирант кафедры эпидемиологии.</p><p>644050, Омск, ул. Мира, 9, тел. 89236786100</p><p> </p></bio><bio xml:lang="en"><p>Alexey I. Blokh – aspirant department of epidemiology.</p><p> </p><p>644050, Omsk, str. Mira, 9. Tel. 89236786100</p></bio><email xlink:type="simple">blokh_ai@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3164-8734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стасенко</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Stasenko</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Леонидович Стасенко – заведующий кафедрой эпидемиологии</p></bio><bio xml:lang="en"><p>Vladimir L. Stasenko – head of the department of epidemiology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Funded Educational Institution for Higher Education «Omsk State Medical University» Ministry of Healthcare of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2018</year></pub-date><volume>17</volume><issue>5</issue><fpage>38</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Блох А.И., Стасенко В.Л., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Блох А.И., Стасенко В.Л.</copyright-holder><copyright-holder xml:lang="en">Blokh A.I., Stasenko V.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/575">https://www.epidemvac.ru/jour/article/view/575</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В последнее десятилетие злокачественные новообразования кожи (ЗНК) рассматриваются как серьёзная угроза здоровью населения. Цель – оценка динамики показателей, характеризующих эпидемиологические проявления меланомы кожи и других ЗНК у населения Алтайского края в 2007–2016 гг., прогноз на последующий период.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Вычислены общие и стандартизованные показатели заболеваемости и общие показатели смертности населения Алтайского края меланомой и другими злокачественными новообразованиями кожи в 2007–2016 гг. Проведён компонентный анализ динамических изменений заболеваемости на протяжении рассматриваемого периода. Проведена оценка риска развития изученной патологии у жителя Алтайского края к возрасту 75, 85 лет и на протяжении жизни. Использован метод нелинейной экстраполяции для расчёта прогноза на последующие десять лет. Результаты. Показатели заболеваемости населения Алтайского края меланомой кожи и другими ЗНК за изученный период составляли 5,7 (95% ДИ 5,4 – 6,0) и 63,4 (95% ДИ 62,4 – 64,4) на 100 тыс. населения соответственно и имели тенденцию к росту (5,2 и 3,1% в год соответственно), что было обусловлено как демографическими процессами (42,1 и 68,6% соответственно), так и широким распространением факторов риска (80,6 и 66,7% соответственно). Риск развития меланомы кожи и другого ЗНК кожи в течение жизни для жителя Алтайского края составил 0,37 и 4,12% соответственно.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. In recent decade, skin cancers are considered as a serious threat to the population health. Goal. Assessment of the dynamics of indicators characterizing the epidemiological manifestations of melanoma and other skin cancers among the population of the Altaiskiy krai in 2007–2016, as well as making a forecast for the next ten-year period.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The general and standardized melanoma and other skin cancers incidence (mortality) rates of the Altaiskiy krai population for the period 2007– 2016 have been calculated. A component analysis of the dynamic changes in morbidity during the studied period was carried out. The risk of development to 75, 85 years old and throughout life of the studied cancers was assessed for a residents of the Altaiskiy krai. The nonlinear extrapolation method was used to calculate the predicted values for the next ten years. Results. The melanoma and other skin cancers incidence rates in the population of Altaiskiy krai in the study period were 5.7 (95% CI 5.4 – 6.0) and 63.4 (95% CI 62.4 – 64.4) per 100 th population and tended to increase (5.2 and 3.1% per year, respectively), which was due to both demographic processes (42.1 and 68.6% respectively), and activation of risk factors (80.6 and 66.7%, respectively). The risk of melanoma and other skin cancer over a lifetime for a resident of the Altaiskiy krai was 0.37 and 4.12%, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, the revealed unfavorable tendencies to the growth of melanoma and other skin cancers morbidity rates in Altaiskiy krai during the studied period testify to the need to improve preventive measures and surveillance.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>злокачественные новообразования кожи</kwd><kwd>меланома кожи</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>skin cancers</kwd><kwd>melanoma</kwd><kwd>preventive measures</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Miller A.J., Mihm M.C.Jr. Melanoma. N. Engl. J. Med. 2006; 355: 51–65.</mixed-citation><mixed-citation xml:lang="en">Miller A.J., Mihm M.C.Jr. Melanoma. N. Engl. J. Med. 2006; 355: 51–65.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ганцев Ш. Х., Юсупов А. С. Плоскоклеточный рак кожи. 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