epidemiologyЭпидемиология и ВакцинопрофилактикаEpidemiology and Vaccinal Prevention2073-30462619-0494«Numicom» LLC10.31631/2073-3046-2018-17-5-100-105epidemiology-583Research ArticleПРАКТИЧЕСКИЕ АСПЕКТЫ ЭПИДЕМИОЛОГИИ И ВАКЦИНОПРОФИЛАКТИКИPRACTICAL ASPECTS OF EPIDEMIOLOGY AND VACCINE PREVENTIONВирус папилломы человека – новый этиологический фактор в развитии рака органов головы и шеи. Проблемы и перспективы их решенияThe Human Papilloma Virus is a New Etiologic Factor in the Development of Cancer of the Head and Neck Organs. Problems and Prospects for their SolutionМудуновА. М.MudunovA. M.

Али Мурадович Мудунов – доктор медицинских наук, профессор, руководитель отдела опухолей головы и шеи.

Ali M. Mudunov – Dr. Sci. (Med), professor head of the of department of head and neck tumor.

Moscow

ali.mudunov@inbox.ruФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава РоссииРоссияN.N. Blokhin National Medical Research Centre of oncologyRussian Federation201823102018175100105Copyright © Мудунов А.М., 20182018Мудунов А.М.Mudunov A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epidemvac.ru/jour/article/view/583

Плоскоклеточный рак органов головы и шеи занимает 5-е место в структуре онкологической заболеваемости в мире. Смертность от этой патологии не меняется на протяжении уже нескольких десятилетий, несмотря на значительные успехи и достижения в современной клинической онкологии. В статье детально рассмотрены и проанализированы: этиологическая роль в развитии рака ротоглотки вируса папилломы человека (ВПЧ); половые и возрастные особенности ВПЧ-ассоциированного рака, различные методы предиктовой диагностики, специфическая профилактика. Сделаны выводы: папилломавирусная инфекция является основной причиной резкого и продолжающегося роста заболеваемости раком ротоглотки в основном среди мужчин во многих странах мира; вакцинация несет позитивные ожидания в профилактике заболеваемости раком ротоглотки.

Squamous cell carcinoma of the head and neck organs occupies the 5th place in the structure of oncological morbidity in the world. The mortality from this pathology has not changed for several decades, despite significant successes and achievements in modern clinical oncology. In article are explored and analyzed: the etiological role of human papillomavirus (HPV) in the development of oropharyngeal cancer; sexual and age specific features of HPV-associated cancer, various methods of predictive diagnosis, specific prevention. Conclusions: papillomavirus infection is the main cause of the sharp and continuing increase in the incidence of oropharyngeal cancer, mainly among men in many countries of the world; vaccination has positive expectations in the prevention of the incidence of oropharyngeal cancer.

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The authors declare that there are no conflicts of interest present.