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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2019-18-2-4-17</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-703</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОБЛЕМНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROBLEM-SOLVING ARTICLE</subject></subj-group></article-categories><title-group><article-title>Три уровня прогнозирования  штаммов вируса гриппа</article-title><trans-title-group xml:lang="en"><trans-title>Three Levels of the Predicting of the Influenza Vaccine Strains</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харченко</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharchenko</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Харченко Евгений Петрович - к. б. н., ведущий научный сотрудник </p><p>194223, Санкт-Петербург, пр. Тореза.</p></bio><bio xml:lang="en"><p> Eugene P. Kharchenko – Dr. Sci. (Biol.), leader researcher.</p><p>194223, Russian Federation, St. Petersburg, Toreza pr., 44. </p></bio><email xlink:type="simple">neuro.children@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУН «Институт эволюционной физиологии и биохимии им. И.М. Сеченова» РАН.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy Sciences.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>29</day><month>04</month><year>2019</year></pub-date><volume>18</volume><issue>2</issue><fpage>4</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Харченко Е.П., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Харченко Е.П.</copyright-holder><copyright-holder xml:lang="en">Kharchenko E.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/703">https://www.epidemvac.ru/jour/article/view/703</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>вирус гриппа</kwd><kwd>прогнозирование</kwd><kwd>эпидсезон</kwd><kwd>пандемия</kwd><kwd>антигенные сайты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>influenza</kwd><kwd>influenza virus strain</kwd><kwd>prediction</kwd><kwd>epidemic season</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Klingen T.R., Reimering S., Guzmán C.A., et al. 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