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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">epidemiology</journal-id><journal-title-group><journal-title xml:lang="ru">Эпидемиология и Вакцинопрофилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Epidemiology and Vaccinal Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-3046</issn><issn pub-type="epub">2619-0494</issn><publisher><publisher-name>«Numicom» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31631/2073-3046-2020-19-2-79-86</article-id><article-id custom-type="elpub" pub-id-type="custom">epidemiology-985</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИЧЕСКИЕ АСПЕКТЫ ЭПИДЕМИОЛОГИИ И ВАКЦИНОПРОФИЛАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICAL ASPECTS OF EPIDEMIOLOGY AND VACCINE PREVENTION</subject></subj-group></article-categories><title-group><article-title>Коклюш в Воронежской области: эпидемиология и вакцинопрофилактика</article-title><trans-title-group xml:lang="en"><trans-title>Pertussis in the Voronezh Region: Epidemiology and Vaccination</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0650-5598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамчик</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamchik</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николай Петрович Мамчик – доктор медицинских наук, профессор, заведующий кафедрой эпидемиологии</p><p>394036, г. Воронеж, ул. Студенческая, 10</p><p>eLibrary SPIN: 7374-0575</p></bio><bio xml:lang="en"><p>Nikolai P. Mamchik – Dr. Sci. (Med.), Professor, Head of the Department of Epidemiology</p><p>Studencheskaya str.10, Voronezh, 394036 </p></bio><email xlink:type="simple">mamchik1949@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5042-3739</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Габбасова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gabbasova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталия Вадимовна Габбасова – доктор медицинских наук, доцент, профессор кафедры эпидемиологии</p><p>394036, г. Воронеж, ул. Студенческая, 10</p><p>eLibrary SPIN: 6629-4401</p></bio><bio xml:lang="en"><p>Nataliya V. Gabbasova – Dr. Sci. (Med.), Professor of the Department ofEpidemiology</p><p>Studencheskaya str.10, Voronezh, 394036 </p></bio><email xlink:type="simple">natalia_gabb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2470-4099</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ситник</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sitnik</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тамара Николаевна Ситник – заместитель главного врача по эпидемиологии Воронежского областного клинического центра профилактики и борьбы со СПИД, ассистент кафедры эпидемиологии Воронежского государственного медицинского университета им. Н. Н. Бурденко</p><p>Воронеж</p><p>eLibrary SPIN: 7431-3504</p></bio><bio xml:lang="en"><p>Tamara N. Sitnik – deputy chief doctor of Voronezh Regional Clinical Center for the Prevention and Control of AIDS, assistant of the Department Epidemiology of Voronezh State Medical University named after N. N. Burdenko</p><p>Voronezh</p></bio><email xlink:type="simple">tnsitnik@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Штейнке</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Steinke</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Васильевна Штейнке – кандидат медицинских наук, ассистент кафедры эпидемиологии Воронежского государственного медицинского университета им. Н. Н. Бурденко, заведующая отделом клинической эпидемиологии Воронежского областного клинического центра профилактики и борьбы со СПИД</p><p>Воронеж</p></bio><bio xml:lang="en"><p>Lyudmila V. Steinke – Cand. Sci. (Med.), assistant of the Department Epidemiology of Voronezh State Medical University named after N. N. Burdenko, Head of the Department of Clinical Epidemiology of the Voronezh Regional Clinical Center for the Prevention and Control of AIDS</p><p>Voronezh</p></bio><email xlink:type="simple">shteinke@aidsvrn.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Воронежский государственный медицинский университет имени Н.Н. Бурденко» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh State Medical University named after N. N. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Воронежский государственный медицинский университет имени Н.Н. Бурденко» Минздрава России;&#13;
БУЗ ВО «Воронежский областной клинический центр профилактики и борьбы со СПИД»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh State Medical University named after N. N. Burdenko;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>16</day><month>05</month><year>2020</year></pub-date><volume>19</volume><issue>2</issue><fpage>79</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мамчик Н.П., Габбасова Н.В., Ситник Т.Н., Штейнке Л.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Мамчик Н.П., Габбасова Н.В., Ситник Т.Н., Штейнке Л.В.</copyright-holder><copyright-holder xml:lang="en">Mamchik N.P., Gabbasova N.V., Sitnik T.N., Steinke L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epidemvac.ru/jour/article/view/985">https://www.epidemvac.ru/jour/article/view/985</self-uri><abstract><sec><title>Резюме</title><p>Резюме. В последние годы, несмотря на высокий охват вакцинацией детского населения, наблюдается рост заболеваемости коклюшем во многих странах мира.</p><p>Целью работы было изучение закономерностей эпидемиологического процесса коклюша в Воронежской области в 2008–2018 гг.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании использовались данные форм федерального государственного статистического наблюдения № 2, 5, 6 за 2008–2018 гг. Статистическую обработку данных проводили с помощью программы Microsoft Excel.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Изучены эпидемиологические особенности коклюша в Воронежской области за длительный период (2008–2018 гг.). Несмотря на высокий охват профилактическими прививками детей первых лет жизни, в последние годы в области заболеваемость коклюшем имела выраженную тенденцию к росту и превысила среднероссийские показатели в 3,5 раза. В возрастной структуре заболевших отмечено увеличение доли школьников и взрослых. Анализ донесений о заболеваемости показал, что половина заболевших была привита в декретированном возрасте, однако интервал после прививки до болезни составил в среднем 9 лет.</p></sec><sec><title>Выводы</title><p>Выводы. В последние годы наметилась тенденция к росту заболеваемости коклюшем в Воронежской области. Заболеваемость привитых указывает на естественное угасание поствакцинального иммунитета к школьному возрасту и требует решения вопроса о введении ревакцинации школьников актуальными ацеллюлярными вакцинами, разработанными на основе циркулирующих штаммов возбудителя.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. In recent years, the increase in the incidence of pertussis has been observed in many countries despite high vaccination coverage of the child population.</p></sec><sec><title>Purpose</title><p>Purpose: was to study the epidemiological features of whooping cough in the Voronezh region for the period from 2008 to 2018 years.</p></sec><sec><title>Methods</title><p>Methods. The research material was data the annual form No. 2, 5, 6 of Rosstat for 2008 through 2018. Statistical data processing was performed using Microsoft Excel 2007.</p></sec><sec><title>Results</title><p>Results. The epidemiological features of pertussis in the Voronezh region for the period from 2008 to 2018 have been studied. Despite the high coverage of preventive vaccinations in children of the first years of life, in recent years, the incidence of pertussis increased the average Russian rates by 3,5 times. In the age structure of the diseased there was a tendency to increase the proportion of schoolchildren and adults. Analysis of the reports showed that half of the cases were vaccinated at the prescribed age, but the interval after vaccination before the illness was an average of 9 years.</p></sec><sec><title>Conclusions</title><p>Conclusions. In recent years, there has been a tendency to an increase in the incidence of whooping cough in the Voronezh region. The incidence of vaccinated indicates the natural extinction of post-vaccination immunity to school age and requires a decision on the introduction of revaccination of schoolchildren with actual acellular vaccines.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>коклюш</kwd><kwd>заболеваемость</kwd><kwd>вакцинация</kwd><kwd>охват прививками</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pertussis</kwd><kwd>whooping cough</kwd><kwd>morbidity</kwd><kwd>vaccination</kwd><kwd>vaccination coverage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сухинин М. В. Коклюш. Требуется новая стратегия диагностики и вакцинопрофилактики. Эпидемиология и вакцинопрофилактика. 2005; 25 (6): 17–21.</mixed-citation><mixed-citation xml:lang="en">Sukhinin M.V. Whooping cough. A new diagnostic and vaccine prevention strategy is required. 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