The Impact of Influenza of Different Etiologies on other ARVI in Children and Adults in 2014 to 2016
https://doi.org/10.31631/2073-3046-2018-17-35-47
Abstract
To assess the relationship between the incidence of influenza and RS, Corona, Metapneumo, Adeno, Paragripp, Rhino and Boca-viral infections, a correlation analysis of cases of influenza and each infection in the age groups of 24 cities of the Russian Federation was carried out. The age structure of infections had significant differences. Among the adult population, influenza was more often detected, more than A(H1N1)pdm09 (61.4%), and ARVI of no influenza etiology – among children 0–2 years, especially Boca-viral and RS-viral (72.5% and 62.8%) infections. The proportion of adults was higher than children aged 3–6 years, with Corona, Rhino and Paragripp infections. The pronounced winter-spring season of influenza was confirmed. RS, Corona and Metapneumo viral infection had a shift at the spring, and Adeno, Paragripp, Boca and Rhino-viral infections – in the autumn. A direct positive correlation between the incidence of influenza in the population as a whole and RS, Corona, Metapneumo, Adeno and Paragripp was shown, but there was no significant correlation with Rhino and Bocaviral infections. The correlation between the adult population and influenza was higher (strong – in RS) and was detected earlier than in children. The duration of correlation with influenza depended on the etiology of ARVI, influenza etiology and age.
About the Authors
L. S. KarpovaRussian Federation
Lyudmila S. Karpova – Dr. Sci. (Med.), (epidemiology), head of the Laboratory of Epidemiology of Influenza and acute respiratory infection at the Research Institute of Influenza.
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812)499 15 33.
K. M. Volik
Russian Federation
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812)499 15 33.
E. A. Smorodintseva
Russian Federation
Elizaveta A. Smorodintseva – Cand. Sci. (Med.), (epidemiology), Leading researcher of the Laboratory for Studying Risk Factors for Influenza and Acute respiratory viral infection at the Research Institute of Influenza.
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812) 499 15 33.
T. P. Stolyarova
Russian Federation
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812)499 15 33.
N. M. Popovtseva
Russian Federation
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812)499 15 33.
K. A. Stolyarov
Russian Federation
197376, St. Petersburg, Prof. Popova str., 15/17; +7 (812)499 15 33.
References
1. Karpova LS, Smorodintseva EA, Sysoeva TI, et al. The Spread of RS-virus Infection and other ARVI not Influenza Etiology in Children and Adults in the Regions of Russia from 2014 to 2016. Epidemiology and Vaccine Prevention. 2018; № 2 (99): 16–26. (In Russ.) doi.org/10.31631/2073-3046-2018-17-2-16-26
2. The instruction for use of а reagents kit for detection causative agents of acute respiratory viral infections of humans. Approved by the Order of Roszdravnadzor from 7/22/2011, No. 4481–Pr/11. (In Russ.)
3. Methodological recommendations for the detection of RNA of influenza A viruses and B and subtyping of the influenza A virus in accordance with the protocol WHO Collaborating Center (CDC, Atlanta USA). Available at: http://www.interlabservice.ru/catalog/reagents/?sid=1437&id=8436 Accessed: 9 Sept 2018.
4. Nazarov MG, editor. Statistics: textbook. 3rd ed. Moscow: KNORUS; 2016. (In Russ.)
5. Kozlov AP, Popov NN. Medical statistics: manual. Kharkiv: HNU center; 2006. (In Russ.)
6. Yunkerov VI, Grigoriev SG. Mathematico-statistical data processing of medical researches. St. Petersburg; 2002. P. 58–74. (In Russ.)
7. Vartanyan RV, Shvetsova YuV, Bunin SV, et al. Bocavirus Infection in Infants. Russian Journal of Children’s Infections. 2010; 9 (3):10–1. (In Russ.)
8. Shkarin VV., Kovalishena OV. New infections, systematization, problems, prospects. Publisher: GEOTAR-Media; 2012. (In Russ.)
9. Edwards KM, Zhu Y, Griffin MR, et al. The burden of human metapneumovirus infection in young children. N Engl J Med. 2013; 368 (7): 633–43.
10. Malova IA, Baranova IP. The Role of a Metapneumovirus and a Bokavirus in Development Acute Respiratory Infections in the hospitalized patients in 2011–2014 years in Penza region. Russian Journal of Children’s Infections. 2016; № 1 (15): 59–63. (In Russ.)
11. Ershov FI, Kiselev OI. Interferons and their inducers (from molecules to drugs). Moscow; 2005. (In Russ.)
12. Isakov VA, Isakov DV, Belyaeva TV, et al. Prospects for the treatment of respiratory infections. Prakticheskaya pulmonologiya. 2015;1:14-20. (In Russ.)
13. García-Sastre A. Induction and evasion of type I interferon responses by influenza viruses. Virus Res. 2011; 162 (0): 12–18. doi:10.1016/j.virusres.2011.10.017
14. Krug RM. Functions of the Influenza A Virus NS1 Protein In Antiviral Defense Curr Opin Virol. 2015; 12: 1–6. doi:10.1016/j.coviro.2015.01.007.
Review
For citations:
Karpova L.S., Volik K.M., Smorodintseva E.A., Stolyarova T.P., Popovtseva N.M., Stolyarov K.A. The Impact of Influenza of Different Etiologies on other ARVI in Children and Adults in 2014 to 2016. Epidemiology and Vaccinal Prevention. 2018;17(6):35-47. (In Russ.) https://doi.org/10.31631/2073-3046-2018-17-35-47