Infectious and Non-infectious Diseases of the Digestive System. Epidemiological Interrelation
https://doi.org/10.31631/2073-3046-2019-18-1-55-66
Abstract
Background. Infectious and non-infectious diseases of the digestive system are common in Russia and worldwide and have major social and economic significance, yet the importance of infectious diseases in development of chronic digestive disorders is not adequately studied. The study aims to define epidemiologic charateristics of non-infectious diseases of the digestive system and to assess the influence of enteric infections on chronic digestive disorders development.
Materials and methods. The authors conducted a retrospective epidemiologic analysis of incidence and prevalence of infectious and non-infectious digestive diseases in Russia in the period between 2002 and 2017 and in-depth for 2010–2017. Statistical analysis was done using least square method, Pearson correlation and regression analysis and statistical processing was performed using the Microsoft Excel and IBM SPSS Statistics software. Findings. During the incidence growth period for non-infectious diseases (2010–2015) in Russia a strong positive correlation is detected between incidences of infectious and non-infectious digestive diseases. In particular, Hepatithis A, Enterovirus, Rotavirus and Norovirus infections have to most significant impact on liver, biliary tract diseases, pancreas and intestinal diseases.
Conclusion. Enteric infections increase the risk of development of chronic digestive diseases. Prevention of infectious diseases will allow to decrease incidence of chronic digestive diseases
About the Authors
M. O. Antipov
Sechenov First Moscow State University, Moscow
Russian Federation
Russian Federation
Maksim O. Antipov – Department of Epidemiology and Evidence-based medicine
119435, Moscow, Bolshaya Pirogovskaya str., 2, 2. +7(903)195-26-62.
A. Ya. Mindlina
Sechenov First Moscow State University, Moscow
Russian Federation
Russian Federation
Alla Yakovlevna Mindlina – Professor of Department of Epidemiology and Evidence-based medicine
119435, Moscow, Bolshaya Pirogovskaya str., 2, 2. +7(916)935-38-51
References
1. Federal State Statistics Service. Number of deaths by main classes of causes of death for 2017; 2017. Available at: http://www.gks.ru/free_doc/new_site/population/demo/demo24.xls Accessed: 5 Dec 2018. (In Russ.)
2. Han SM, Duggan CP, Graham DA. Understanding the Burden of Pediatric Gastrointestinal Diseases-How-to-Do-It-Yourself. J Pediatr. 2018;194:11–12.
3. Briko NI. The main tenets of the modern epidemiology paradigm. Medical Almanac. 2017;4(49). (In Russ.)
4. Luppov DS, Krasnikov AA, Makhmutova ER, Shubin LL. Analysis of the incidence of diseases of the digestive organs in the Udmurt Republic in 2011–2015. Synergy of Sciences. 2016;6:770–777. (In Russ.)
5. Smagina N. Analysis of the incidence of gastric ulcer and duodenal ulcer in the Chelyabinsk region, predicting the dynamics of its development. Ural Medical Journal. 2010:90–95. (In Russ.)
6. Lezhnev IYu, Balabina NM. The prevalence and risk factors of chronic gastritis. Siberian Medical Journal. 2011;4:31–33. (In Russ.)
7. Glavnov PV, et al. Ulcerative colitis and Crohn’s disease. The current state of the problem of etiology, early diagnosis and treatment (literature review). SPbSU Bulletin. 2015;4:48–72. (In Russ.)
8. Ivashkin VT, et al. The prevalence of non-alcoholic fatty liver disease in patients of outpatient practice in the Russian Federation: the results of the DIREG 2 study. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2015;6:31–41. (In Russ.)
9. Saurina OS, Mamoshina IV, Mamoshin AV. Analysis of the incidence of acute pancreatitis in the Oryol region. Uchenye zapiski Oryol State University. Series: Natural, Technical and Medical Sciences. 2012;6–1:322–326. (In Russ.)
10. Kappelman MD, Moore KR, Allen JK, Cook SF. Crohn’s disease and ulcerative colitis in a commercially insured US population. Dig Dis Sci. 2013;58(2):519–25.
11. Kappelman MD, et al. Crohn’s disease prevalence and geographic distribution of the United States. Clin Gastroenterol Hepatol. 2007;5(12):1424–9.
12. Nader LA, de Mattos AA, Bastos GA. Burden of liver disease in Brazil. Liver Int. 2014;34(6):844–9.
13. Vernon G, Baranova A, Younossi ZM. Non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther. 2011;34(3):274–85.
14. Satapathy SK, Sanyal AJ. Epidemiology and Natural History of Fatty Liver Disease. Semin Liver Dis. 2015;35(3):221–35.
15. Nesvaderani M, Eslick GD, Vagg D, et al. Epidemiology, aetiology and outcomes of pancreatitis: A retrospective cohort study. Int J Surg. 2015;23(Pt A):68–74.
16. Yadav D, Lowenfels AB. The Epidemiology of Pancreatitis and Pancreatic Cancer. Gastroenterology. 2013;144(6):1252–1261.
17. Uchaikin VF, Kovalev OB, Molochkova OV, Cherednichenko TV. Long-term effects of hepatitis A in children. Children’s infections. 2014;3. Available at: https://cyberleninka.ru/article/n/otdalennye-posledstviya-gepatita-a-u-detey Accessed: 5 Dec 2018. (In Russ.)
18. Uchaikin VF, Talalaev AG, Novikova AV, Levitsky MV. The role of rotaviruses in chronic gastroenterological pathology in children. Pediatric infections. 2003;1:10–12. (In Russ.).
Review
For citations:
Antipov M.O., Mindlina A.Ya. Infectious and Non-infectious Diseases of the Digestive System. Epidemiological Interrelation. Epidemiology and Vaccinal Prevention. 2019;18(1):55-66. (In Russ.) https://doi.org/10.31631/2073-3046-2019-18-1-55-66
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