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Determination of Approaches to the Epidemiological Surveillance of Intraamniotic Infection of the Fetus

https://doi.org/10.31631/2073-3046-2020-19-1-83-89

Abstract

In recent years, there has been a steady increase in the number of infections specific to the perinatal period, wth 60% of the perinatal infections in St. Petersburg being intra-amniotic infections (IAI) of the fetus.

The aim of the study is to identify the frequency and risk factors of Intra-amniotic infection of fetus, not elsewhere classified (ICD-10 code P39.2).

Materials and methods. The study, conducted in a maternity hospital in St. Petersburg, included 240 newborns wth clinically established diagnoses from the P39 group «Other infections specific to the perinatal period».

Results of the study. A definition of the case of IAI of the fetus, not elsewhere classified (ICD-10 code P39.2), was proposed - the presence of IAI signs in the histological study of the placenta and the presence of a systemic inflammatory response in a newborn child. Using the definition of a confirmed case the frequency of fetal IAI was 0.42 per 100 children live-born, which is 3.5 times lower than the frequency of clinically determined diagnoses. Risk factors for the confirmed case were: asymptomatic bacteriuria, pyelonephritis, colpitis, tonsilltis, cervical erosion in the history of cervical anamnesis, cardiovascular diseases in the mother.

Conclusion. In the course of epidemiological surveillance of intra-amniotic infection of the fetus, it is necessary to use the definition of the case with further stratification of data on the newborn's body weight at birth. In order to reduce the incidence of this pathology, it is necessary to develop programs aimed at identifying and eliminating factors that increase the risk of maternal and fetal IAI.

About the Authors

M. D. Zlokazov
North-West State Medical Unversity named after 1.1. Mechnikov; Maternity Hospital №10
Russian Federation

Mikhail D. Zlokazov - post-graduate student of the Department of Epidemiology, Parasitology and Disinfectology.

41, str. Kirochnaya, St. Petersburg, 191015, +7-911-011-77-73



A. V. Lyubimova
North-West State Medical Unversity named after 1.1. Mechnikov
Russian Federation

Anna V. Lyubimova - Dr. Sci. (Med.), associate professor of the Department of Epidemiology, Parasitology and Disinfectology.

41, str. Kirochnaya, St. Petersburg, 191015, +79062448322



L. A. Ivanova
Maternity Hospital №10
Russian Federation

Lada A. Ivanova- Cand. Sci. (Med.), Chief Physician.

21, st. Tambasova, St. Petersburg, 198259, +7-921-999-90-39



I. S. Bazaeva
Maternity Hospital №16
Russian Federation

Irina S. Bazaeva – epidemiologist.

54, str. Malaya Balkanskaya, St. Petersburg, 192283, +7-921874-74-40



T. V. Os'mirko
North-West State Medical Unversity named after 1.1. Mechnikov
Russian Federation

Tatyana V. Osimirko - Cand. Sci. (Med.), associate professor of the Department of Epidemiology, Parasitology and Disinfection.

41, str. Kirochnaya, St. Petersburg, 191015, +79216407791



А. G. Komissarov
Cty Polyclinic No. 75
Russian Federation

Anton G. Komissarov - bacteriologist of bakteiologicheskaya laboratory.

22a str. Frunze, St. Petersburg 196135, +7-911-946-46-57



References

1. O sostoyanii sanitarno-epidemiologicheskogo blagopoluchiya naseleniya v Rossijskoj Federacii v 2018 godu: State report. Moscow. Federal Service for Supervision of Consumer Rights Protection and Human Welfare. 2019: 254. Available at: https://rospotrebnadzor.ru/upload/iblock/798/gosudarstvennyy-doklad-o-sostoyanii-sanitarno_epidemiologicheskogo-blagopoluchiya-naseleniya-v-rossiyskoy-federatsii-v-2018-godu.pdf (In Russ).

2. Order of the Ministry of Health and Social Development of the Russian Federation (Ministry of Health and Social Development of Russia) dated December 27, 2011 N 1687n Moscow «0 medicinskih kriteriyah rozhdeniya, forme dokumenta o rozhdenii i poryadke ego vydachi». Available at: https://rg.ru/2012/03/23/kriterii-rozhd-dok.html. Accessed: 04 July 2019 (In Russ).

3. Zlokazov MD, Liubimova AV, Tekhova IG et al. The Problems of detection and registration of infections specific to the perinatal period in neonates. Epidemiology and Vaccinal Prevention. 2018; 17 (5): 71-7 (in Russ). doi: 10.31631/2073-3046-2018-17-5-71-77

4. Gibbs RS, Castillo MS, Rodgers PJ. Management of acute chorioamnionitis. Am J Obstet Gynecol. 1980; 136 (6); 709-13. doi: 10.1016/0002-9378(80)90445-7.

5. Lyubimova A V, Zueva LP, Kyanksep AN, at al. Kriterii otneseniya novorozhdennykh v gruppu vysokogo riska po raz vitiyu infektsij i diagnostiki vnutriamnioticheskoj infektsii ploda i ikh otsenka. Meditsinskij al'monakh. 2015; 5 (40): 83-85 (In Russ).

6. Zerani JR, McGee L, Schrag SJ. Prevention of perinatal group B streptococcal disease-revised guidelines from CDC. Division of Bacterial Diseases. 2010; 59 (10): 1-36.

7. Heine RP, Puopolo KM, Beigi R, at al. Intrapartum management of intraamniotic infection. ACOG committee opinion. 2017; 130 (2): e95 -101. doi: 10.1097/AOG.0000000000002236.

8. Horvath B, Lakatos F, Toth C, at al. Silent chorioamnionitis and associated pregnancy outcomes: a review of clinical data gathered over a 16-year period. J Perinat Med. 2014; 42 (4): 441-47. doi: 10.1515/jpm-2013-0186.

9. Zynn H, Wong T, Matthew J, at al. Time for a neonatal specific consensus definition for sepsis. Pediatric care. 2014; 15 (6):523-528. doi: 10.1097/PCC.0000000000000157.


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For citations:


Zlokazov M.D., Lyubimova A.V., Ivanova L.A., Bazaeva I.S., Os'mirko T.V., Komissarov А.G. Determination of Approaches to the Epidemiological Surveillance of Intraamniotic Infection of the Fetus. Epidemiology and Vaccinal Prevention. 2020;19(1):83-89. (In Russ.) https://doi.org/10.31631/2073-3046-2020-19-1-83-89

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ISSN 2073-3046 (Print)
ISSN 2619-0494 (Online)