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Multi-Level Monitoring of Vaccination Adherence of Various Population Groups in the Context of the COVID-19 Pandemic: Problematic Issues

https://doi.org/10.31631/2073-3046-2021-20-6-28-36

Abstract

Relevance. Despite significant progress in the prevention of many infectious diseases, a number of organizational issues remain in the area of special attention. One of them is to ensure the timeliness and completeness of vaccination coverage in the decreed age groups, which is possible only with a high level of public commitment to vaccination. During the pandemic of the new coronavirus infection (COVID-19), achieving a high level of vaccination coverage of the National Calendar of Preventive vaccinations is of particular relevance. Aim. Using state-of-the-art online resources, assess population vaccination adherence to develop effective communication risk management technologies for immunoprophylaxis in the COVID-19 pandemic. Materials and methods. To assess the commitment of various population groups and professional contingents of a large industrial city to vaccine prevention, a survey of 965 parents was conducted at the initial stage, and subsequently a survey of 2,632 employees of medical organizations, including 1,422 people in the period before the COVID - 19 pandemic, 572 people in the «first wave» of the pandemic and 638 people in the «second wave». Instagram Facebook, Instagram, and VKontakte social networks were used to quickly obtain the necessary information (Google forms, corporate e-mails, WhatsApp, Telegram messengers, etc.). The work uses epidemiological, sociological and statistical methods of research. Results and discussion. When assessing the attitude of parents to vaccination, it was found that 78.8% of respondents were positive about vaccinations, 14.6% doubted their effectiveness and safety, and 6.6% denied their need. The main source of information that forms the attitude to vaccinations of parents was the opinion of medical professionals. In a survey of 1,422 employees, 190 people (13.3%) were identified, mainly from among the trained specialists, who themselves had a negative attitude to vaccination. When assessing the commitment of employees of medical organizations to the vaccination of a new coronavirus infection, the attitude to vaccination was ambiguous, especially in the group of secondary medical personnel and female employees of non-medical specialties, who are a potential risk group for forming a negative attitude to vaccinations and can act as «opinion leaders» on this issue for other categories of the population. Insufficient adherence to COVID-19 vaccine prevention has also been observed in other countries among various population groups, which is a serious problem on a global scale, hindering the fight against the pandemic of a new disease, which requires corrective measures. Conclusion. In this study, using modern online resources, a rapid assessment of the vaccination adherence of various population groups (parents and medical professionals) was carried out. It is shown that the use of modern technologies and software tools makes it possible to analyze a large array of data to solve problems of overcoming communication risks. The results obtained point to the need for prompt corrective measures in terms of the introduction of educational programs to increase adherence to vaccination, especially in groups at potential risk of the disease, including medical professionals, which is a priority for health care in all countries.

About the Authors

A. A. Golubkova
Central research Institute of epidemiology of Rospotrebnadzor; Russian Medical Academy of Continuing Professional Education
Russian Federation

Alla A. Golubkova – Dr. Sci. (Med.), Professor, leading researcher of the laboratory of infections associated with the provision of medical care of Central research Institute of epidemiology of Rospotrebnadzor; professor of the Department of Epidemiology of Russian Medical Academy of Continuing Professional Education

111123, Moscow, Novogireevskaya str., 3A;
125993, Moscow, Barrikadnaya str., building 1   
Tel. +7 (912) 617-39-85



T. A. Platonova
European medical center «UMMC-Health»
Russian Federation

Tatyana A. Platonova – Cand. Sci. (Med.), head of the epidemiological Department - epidemiologist

620144, Yekaterinburg, Sheinkmana str.
Tel. +7 (343) 344-27-67, *1894, +7 (982) 691-88-30



T. A. Semenenko
The National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya of the Ministry of Healthcare the Russian Federation; I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Healthcare the Russian Federation
Russian Federation

Semenenko Tatyana Anatolyevna – Dr. Sci. (Med.), Head of the Epidemiology Department of the National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya of the Ministry of Healthcare of the Russian Federation; Professor of the Department of Infectology and Virology of I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Healthcare the Russian Federation

123098, Moscow, Gamalei str., 18;
119991, Moscow, Trubetskaya str., 8/2
Tel. +7 (499) 190-72-56



S. S. Smirnova
ERIVI, FBRI SRC VB «Vector», Rospotrebnadzor; Ural state medical University
Russian Federation

Svetlana S. Smirnova – Cand. Sci. (Med.), head of the Ural-Siberian Scientific and Methodological Center for the Prevention of Infections Associated with the Provision of Medical Assistance, Ekaterinburg Research Institute of Viral Infections of ERIVI, FBRI SRC VB «Vector», Rospotrebnadzor; associate Professor of the Department of epidemiology, social hygiene and organization of Ural state medical University of the Ministry of Healthcare of the Russian Federation

620030, Ekaterinburg,  Letnyaya str., 23;
620028, Ekaterinburg, Repin str., 3
Tel. +7 (343) 261-99-47 (*106), +7 (908) 917-59-8



A. D. Nikitskaya
City Clinical Hospital No. 1 named after N.I. Pirogov
Russian Federation

Anna D. Nikitskaya – epidemiologist

117049, Moscow, Leninsky prospect, 8
Tel. +7 (906) 751-23-44



M. V. Chikunova
Ural state medical University
Russian Federation

Marina V. Chikunova – Cand. Sci. (Med.), associate Professor of the Department of faculty therapy and geriatrics

620028, Yekaterinburg, Repin str., 3  
Tel. +7 (950) 641-11-14



References

1. Briko N.I., Tsapkova N.N., Batyrshina L.R., Korshunov V.A., Feldblyum I.V., Bikmieva A.V., et al. Problems of Vaccinal Prevention in Adult Population. Epidemiology and Vaccinal Prevention. 2018;17(2):4–15 (In Russ.) https://doi.org/10.31631/2073-3046-2018-17-2-4-15

2. Briko N.I., Feldblyum I.V. The Modern Concept of Development of Vaccine Prevention in Russia. Epidemiology and Vaccinal Prevention. 2019;18(5):4–13. (In Russ.) https://doi.org/10.31631/2073-3046-2019-18-5-4-13

3. Briko N.I. Evaluation of the quality and effectiveness of immunoprophylaxis. Medical scientific and methodological portal «Attending physician». Available at: https://www.lvrach.ru/2012/10/15435557/ (viewed May 15, 2021) (In Russ.).

4. Tatochenko V.K., Ozeretskovsky N.A., Fedorov A.M. Immunoprophylaxis-2014 (reference book). Moscow: Pediatrician; 2018:272. (In Russ.).

5. Galina N.P., Mindlina A.Y., Polibin R.V. Surveying children and adult vaccination program against diphtheria, tetanus, measles and viral hepatitis B in the Russian Federation. Russian. Journal of Infection and Immunity. 2019;9(5–6):779–786 (In Russ.). https://doi.org/10.15789/2220-7619-2019-5-6-779-786

6. Platonova T.A., Golubkova A.A., Koltunova E.S., Smirnova S.S., Abdulvalieva V.V., Kuznezova O.A. National Vaccination Shedule: Quality of Performance and Determining Factors. Epidemiology and Vaccinal Prevention. 2019;18(2):97–103 (In Russ.). https://doi.org/10.31631/2073-3046-2019-18-2-97-103

7. Bayanova T.A., Petrova A.G., Vanyarkina A.S., Kupriyanova N.Yu., Gavrilova T.A. Adherence Population to Vaccination of Influenza: Survey Results. Epidemiology and Vaccinal Prevention. 2021;20(1):69–75 (In Russ.). https://doi.org/10.31631/2073-3046-2021-20-1-69-75

8. Platonova T.A., Koltunova E.S., Golubkova A.A., Zhilyaeva I.V., Abdulvalievai V.V. Practical issues of vaccination of children in a polyclinic. Pacific Medical Journal. 2018;(3):33– 37. (In Russ.). https://doi.org/10.17238/PmJ1609-1175.2018.3.33-37

9. Ermolenko K.D., Kharit S.M., Ruleva A.A., Drozdova L.Yu. Establishing a Dialogue with a Patient on Vaccination (Scientific Review). Epidemiology and Vaccinal Prevention. 2021;20(1):114–124 (In Russ.). https://doi.org/10.31631/2073-3046-2021-20-1-114-124

10. Ghomi R., Asgari N., Hajiheydari A., Esteki R., Biyabanaki F., Nasirinasab F. The COVID-19 pandemic: a systematic review of the current evidence. Russian Journal of Infection and Immunity. 2020;10(4):655–663 (In Russ.). https://doi.org/10.15789/2220-7619-TCP-1508

11. Shchelkanov M.Yu., Kolobukhina L.V., Burgasova O.A., Kruzhkova I.S., Maleev V.V. COVID-19: etiology, clinical picture, treatment. Russian Journal of Infection and Immunity. 2020;10(3):421–445 (In Russ.). https://doi.org/10.15789/2220-7619-CEC-1473

12. Briko N.I., Kagramanyan I.N., Nikiforov V.V., Suranova T.G., Chernyavskaya O.Р., Polezhaeva N.A. Pandemic COVID-19. Prevention Measures in the Russian Federation. Epidemiology and Vaccinal Prevention. 2020;19(2):4–12 (In Russ.). https://doi.org/10.31631/2073-3046-2020-19-2-4-12

13. World Health Organization Guidelines of March 26, 2020 «Guidelines for immunization activities during the COVID-19 pandemic»

14. Logunov DY, Dolzhikova IV, Zubkova OV, Tukhvatulin AI, Shcheblyakov DV, Dzharullaeva AS, et al. Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia. Lancet. 2020 Sep 26;396(10255):887–897. doi: 10.1016/S0140-6736(20)31866-3.

15. Logunov DY, Dolzhikova IV, Shcheblyakov DV, Tukhvatulin AI, Zubkova OV, Dzharullaeva AS, et al. Gam-COVID-Vac Vaccine Trial Group. Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia. Lancet. 2021 Feb 20;397(10275):671–681. doi:10.1016/S0140-6736(21)00234-8.

16. Kharchenko E.P. Vaccines against Covid-19: the Comparative Estimates of Risks in Adenovirus Vectors. Epidemiology and Vaccinal Prevention. 2020;19(5):4–17 (In Russ.). https://doi.org/10.31631/2073-3046-2020-19-5-4-17

17. Ryzhikov A.B., Ryzhikov Е.А., Bogryantseva M.P., Usova S.V., Danilenko E.D., Nechaeva E.A., et al. A single blind, placebo-controlled randomized study of the safety, reactogenicity and immunogenicity of the «EpiVacCorona» Vaccine for the prevention of COVID-19, in volunteers aged 18–60 years (phase I–II). Journal of Infection and Immunity. 2021;11(2):283–296 (In Russ.). https://doi.org/10.15789/2220-7619-ASB-1699

18. Palamenghi L, Barello S, Boccia S, Graffigna G. Mistrust in biomedical research and vaccine hesitancy: the forefront challenge in the battle against COVID-19 in Italy. Eur J Epidemiol. 2020 Aug;35(8):785–788. doi:10.1007/s10654-020-00675-8.

19. Wang J, Lu X, Lai X, Lyu Y, Zhang H, Fenghuang Y, et al. The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study. Vaccines (Basel). 2021 Feb 25;9(3):191. doi:10.3390/vaccines9030191

20. Fisher KA, Bloomstone SJ, Walder J, Crawford S, Fouayzi H, Mazor KM. Attitudes Toward a Potential SARS-CoV-2 Vaccine : A Survey of U.S. Adults. Ann Intern Med. 2020 Dec 15;173(12):964–973. doi:10.7326/M20-3569.

21. Bendau A, Plag J, Petzold MB, Ströhle A. COVID-19 vaccine hesitancy and related fears and anxiety. Int Immunopharmacol. 2021 Apr 27;97:107724. doi:10.1016/j.intimp.2021.107724.

22. Qattan AMN, Alshareef N, Alsharqi O, Al Rahahleh N, Chirwa GC, Al-Hanawi MK. Acceptability of a COVID-19 Vaccine Among Healthcare Workers in the Kingdom of Saudi Arabia. Front Med (Lausanne). 2021 Mar 1;8:644300. doi:10.3389/fmed.2021.644300.

23. Biswas N, Mustapha T, Khubchandani J, Price JH. The Nature and Extent of COVID-19 Vaccination Hesitancy in Healthcare Workers. J Community Health. 2021 Apr 20:1–8. doi:10.1007/s10900-021-00984-3.


Review

For citations:


Golubkova A.A., Platonova T.A., Semenenko T.A., Smirnova S.S., Nikitskaya A.D., Chikunova M.V. Multi-Level Monitoring of Vaccination Adherence of Various Population Groups in the Context of the COVID-19 Pandemic: Problematic Issues. Epidemiology and Vaccinal Prevention. 2021;20(6):28-36. (In Russ.) https://doi.org/10.31631/2073-3046-2021-20-6-28-36

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ISSN 2073-3046 (Print)
ISSN 2619-0494 (Online)