Study of the Effectiveness against Test Strain Mycobacterium terrae DSM 43227 of Some Substances Containing Fragment of Phenolic
https://doi.org/10.31631/2073-3046-2016-15-4-37-41
Abstract
Relevance. Multi-drug-resistant Mycobacterium tuberculosis has been an important problem in public health around the world. However, development of effective methods and means of disinfection is now extremely urgent. Phenol is probably the oldest known disinfectant. Disinfectants based on substances containing phenolic practically used in almost every countries of the worldwide for the disinfection of medical devices, surfaces and hand hygiene. Goal. Comparative study of the activity of certain disinfectants containing phenol fragment against the test strain. Materials and methods. Multi-drug-resistant M. terrae, M. avium-intracellulara and M. tuberculosis have similar characteristics of resistance to chemical disinfectants, herefore M. terrae DSM 43227 used as the test strain. We studied five used in Russia for the production of disinfectants and antiseptics. substances containing a phenolic. Results. The disinfectant effect of substances with phenol compounds was detected in lower concentrations (from 0.02% for 2-benzil-4-chlorphenol to 1.0% for ortophenylphenol) than with substances containing glutaraldehyde or chloramine B compounds. Conclusions. Saving disinfecting effectiveness at low concentrations of the active substances in the working solutions can be recommended disinfectants based on phenolic compounds for disinfection measures in the complex of measures for prevention of occurrence and spread of tuberculosis.
About the Authors
T. A. Grenkova
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Russian Federation
Russian Federation
A. I. Chizhov
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Russian Federation
Russian Federation
M. P. Gusarova
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Russian Federation
Russian Federation
N. V. Gudova
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Russian Federation
Russian Federation
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Review
For citations:
Grenkova T.A., Chizhov A.I., Gusarova M.P., Gudova N.V. Study of the Effectiveness against Test Strain Mycobacterium terrae DSM 43227 of Some Substances Containing Fragment of Phenolic. Epidemiology and Vaccinal Prevention. 2016;15(4):37-41. (In Russ.) https://doi.org/10.31631/2073-3046-2016-15-4-37-41
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