The Epidemiological Situation with Pertussis in the Yaroslavl Region and its Development Trends

Abstract

Relevance. The problem of pertussis infection remains relevant, since the epidemic process at the present stage continues to involve both unvaccinated young children, schoolchildren vaccinated against this infection with lost immunity, and adults with an unknown diagnosis of pertussis.
Aims. The problem of pertussis infection remains relevant, since at the present stage, both unvaccinated young children, as well as schoolchildren with lost immunity vaccinated against this infection, and adults with an unspecified diagnosis of pertussis continue to be involved in the epidemic process.
Material & Methods. The study used data from the epidemiological surveillance of whooping cough presented in the state reports «On the state of sanitary and epidemiological welfare of the population in the Yaroslavl region» of the Office of Rospotrebnadzor in the Yaroslavl region, in the Russian Federation, the federal statistical observation form No. 2 «Information on infectious and parasitic diseases» and the medical history of whooping cough patients hospitalized in the GUZ YAO Regional Clinical Infectious Diseases Hospital" in 2023.
Results. The data was processed using the MS Excel 2016 software. The significance of the mathematical model was tested using the Fisher criterion. To assess statistical reliability, a table of critical values of the Fisher criterion was used, the significance level was assumed to be α = 0.05.
Conclusions. In order to reduce the incidence of pertussis, it is necessary to increase the coverage and timeliness of immunization against whooping cough in children, make adjustments to the Regional Calendar of preventive vaccinations and improve health awareness work.