Molecular Epidemiology of Rabies Virus in the Territory of the Russian Federation
https://doi.org/10.31631/2073-3046-2017-16-1-39-42
Abstract
In this study, we report the phylogenetic relationship of RABV circulating in Russia. A total of 81 new isolates obtained from different regions of Russia in 2008 - 2016 were partially sequenced. Evolutionary analysis based on 100 representative sequences of rabies virus N-gene fragments (1110 nt) with sample time span ranging from 1977 to 2016 was made by the Bayesian coalescent analysis. Temporal estimates for major evolutionary events were done. The division of steppe rabies virus group C to discrete subgroups was revealed. According to our data, this most widespread in the Russian Federation group emerged in the beginning of the 1940th. The presence of steppe rabies virus was detected in the Far East (Primorsky Krai). The most likely cause of this event is anthropogenic introduction.. For the first time, representatives of arctic rabies subgroup A2 were isolated in the north of European Russia and FranzJosef Land. Evolutionary analysis suggested relatively recent emergence of all rabies virus groups currently circulating in the territory of the Russian Federation.
About the Authors
A. A. Deviatkin
Federal Budget Institution of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; Federal State Budget Institute of Science «Chumakov Institute of Poliomyelitis and Viral Encephalitides»; Federal State Budget Institute of Science «Research Institute of Occupational Health»
Russian Federation
Russian Federation
A. N. Lukashev
Federal State Budget Institute of Science «Chumakov Institute of Poliomyelitis and Viral Encephalitides»
Russian Federation
Russian Federation
E. M. Poleshchuk
Federal Budget Institution of Science «Institute for Natural Foci Infections»
Russian Federation
Russian Federation
S. E. Tkachev
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
V. G. Dedkov
Federal Budget Institution of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; Federal State Budget Institute of Science «Chumakov Institute of Poliomyelitis and Viral Encephalitides»
Russian Federation
Russian Federation
G. N. Sidorov
Federal Budget Institution of Science «Institute for Natural Foci Infections»; Federal Budget Institution of Science «Omsk State Pedagogical University
Russian Federation
Russian Federation
M. Yu. Shchelkanov
State Autonomous Educational Institution of Higher Professional Education «Far Eastern Federal University»
Russian Federation
Russian Federation
I. V. Galkina
State Autonomous Educational Institution of Higher Professional Education «Far Eastern Federal University»
Russian Federation
Russian Federation
G. G. Karganova
Federal State Budget Institute of Science «Chumakov Institute of Poliomyelitis and Viral Encephalitides»
Russian Federation
Russian Federation
M. V. Gavrilo
Federal State Budget Institute «National Park «Russian Arctic»
Russian Federation
Russian Federation
G. A. Shipulin
Federal Budget Institution of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation
Russian Federation
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Review
For citations:
Deviatkin A.A., Lukashev A.N., Poleshchuk E.M., Tkachev S.E., Dedkov V.G., Sidorov G.N., Shchelkanov M.Yu., Galkina I.V., Karganova G.G., Gavrilo M.V., Shipulin G.A. Molecular Epidemiology of Rabies Virus in the Territory of the Russian Federation. Epidemiology and Vaccinal Prevention. 2017;16(1):39-42. (In Russ.) https://doi.org/10.31631/2073-3046-2017-16-1-39-42
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