Epidemiology of Healthcare-Associated Infections, Coused by Sapronoses Group Pathogens

Sapronoses group pathogens are characterized by highly epidemic features and play a significant role in healthcare-associated infections (HAIs). They can be responsible for outbreaks and severe infections with high mortality and disability of patients. Their share in the etiological structure of HAIs reaches 30%. The most actual sapronoses group pathogens causing HAIs includes Legionella spp., Pseudomonas spp., Serratia spp. and Clostridium spp. The article discusses the taxonomy, ecology pathogenicity factors and reservoir, particularly sources of infection, factors and ways of pathogens transmission in healthcare settings. The prevention and control measures are systematized.

инфекции, связанные с оказанием медицинской помощи , сапронозы, систематика, экология, факторы патогенности, резервуар, источники, пути и факторы передачи возбудителей инфекций, профилактические и противоэпидемические меры, healthcare-associated infections , sapronoses , taxonomy , ecology , pathogenicity factors , reservoir , sources , factors and ways of pathogens transmission , prevention and control measures

1. Brusina E.B., Leverage I.P. Epidemiology of nosocomial septic infections in surgery. Novosibirsk. Science. 2006: 168 (in Russian).

2. Briko N.I., Brusin E.B., Zuevф L.P., Kovalishena O.V., Ryapis L.A., Stasenko V.L. et al. Hospital strains – the unknown reality. Epidemiology and Vaccine Prevention. 2013; 1 (68): 30 – 35 (in Russian).

3. Tartakovsky I.S., Gruzdeva O.A., Galstyan G.M., Karpov T.I. Prevention, diagnosis and treatment legionellezis. Moscow: Studio MDAs; 2013: 344 (in Russian).

4. Pavlova O.N. Bacteria of the genus Pseudomonas in the microbial community of Lake Baikal: Abstract. dis. ... doctorat of biol. sci. Irkutsk; 2004: 23 (in Russian).

5. Euzеby J.P. List of prokaryotic names with standing in nomenclature. Доступно на: InternetInt J. Syst. Bacteriol. April. 1997; 47: 590 – 592. Doi: 10.1099/00207713-47-2-590.

6. Yutin N., Galperin Y.M. A genomic update on clostridial phylogeny: Gram-negative spore-formers and other misplaced clostridia. Environ. Microbiol. 2013; 15 (10): 2631 – 2641.

7. Greub G., Raoult D. Microorganisms resistant to free-living amoebae. Clin. Microbiol. Rev. 2004. 17 (2): 413 – 433.

8. Grimont F., Grimont P. The Genus Serratia. In: The Procariotes. 2006: 219 – 244.

9. Michel R., Burghardt H., Bergmann H. Acanthamoeba, naturally intracellularly infected with Pseudomonas aeruginosa, after their isolation from a microbiologically contaminated drinking water system in a hospital. Zentralbl. Hyg. Umweltmed. 1995; 196: 532 – 544.

10. Hume R.D., Hann W.D. Growth relationships of Legionella pneumophila with green algae (Chlorophyta), in Legionella. Proceedings of the 2nd International conference. Еds.: Thornsberry C., Balows A., Feeley J.C. and Jakubowski W. Washington, BC: American Society of Microbiology. 1984a: 323, 324.

11. Baryshnikov L.M., Grishchenkov V.G., Arinbasarov M.U., Shkidchenko A.I., Voronin A.I. Biodegradation of oil -destruktorami strains and their associations in a liquid medium. Applied Biochemistry and Microbiology. 2001; 37 (5): 542 – 550 (in Russian).

12. The strain of the bacteria Pseudomonas aeruginosa, decomposing formaldehyde. Patent RU2064018 (in Russian).

13. Brusina E.B., Richagov I.P. Prevention of nosocomial septic infections in surgical hospitals: a new look at an old problem. Epidemiology and Infections Diseases. 2006; 1: 18 – 21 (in Russian).

14. Parеs Y. Action de Serratia marcescens dans le cycle biologique des métaux. Annales de l’Institut Pasteur. 1964; 107: 136 – 141.

15. Skaliy P., McEachern H.V. Survival of leggionaries’ disease bacterium I water. Ann. Intern. Med. 1979; 90: 622 – 663.

16. Brook I. Сlostridium species ( Clostridium perfringens, C. butyricum, C. clostridioforme, C. innocuum, C. ramosum, C. septicum, C. sordellii, C. tertium). Available at: http://www.antimicrobe.org/b90.asp

17. Costerton J.W. Overwiev of microbial biofilms. J. Industr. Microbiol. 1995; 15: 137 – 140.

18. Kuznetsova M.V. Microbiology Pseudomonas nosocomial infection: prevalence monitoring, biological characteristics of the pathogen, and new approaches to diagnosis: PhD of med. sci. diss. Perm’; 2014: 45 (in Russian).

19. States S.J., Conley L.F., Ceraso M. Stephenson T.E., Randy S., Wadowsky R.M. et al. Effects of metals on Legionella pheumophila growth in drinking water plumbing systems. Appl. Environ. Microbiol. 1985; 50 (5): 1149 – 1154.

20. Cateau E., Delafont V., Hechard Y., Rodier M.H. Free-living amoebae: what part do they play in healthcare-associated infections? J. Hosp. Infect. 2014; 87 (3): 131 – 140.