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The Action of inVestigational Drugs of Brucella abortus in the L- and S-forms on the Subpopulations of Blood Cells and Peritoneal Fluid of White Mice (Communication 2)

https://doi.org/10.31631/2073-3046-2015-14-2-102-106

Abstract

We have estimated the effects of the Brucella abortus 19 ВА inactivated vaccine, thermo extracts of Brucella abortus I-206 in the L- and S-forms and corpuscular antigen of Brucella abortus I-206 in L-form on the population and subpopulation structure of blood cells and peritoneal fluid of white mice. It was showed that the antigen preparations of Brucella abortus I-206 in L-form didn't caused endogenous intoxication of the organism of experimental animals in distinction from the inactivated vaccine of Brucella abortus 19 BA.

About the Authors

S. A. Vityazeva
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


T. P. Starovoitova
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


V. I. Dubrovina
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


L. M. Mikhailov
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


K. Yu. Yastremskaya
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


L. E. Tokareva
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


N. L. Barannikova
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


S. V. Balakhonov
Irkutsk Antiplague Research Institute of Siberia and the Far East of IFederal Service on Customers’ Rights Protection and Human Well-Being Surveillance
Russian Federation


References

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Review

For citations:


Vityazeva S.A., Starovoitova T.P., Dubrovina V.I., Mikhailov L.M., Yastremskaya K.Yu., Tokareva L.E., Barannikova N.L., Balakhonov S.V. The Action of inVestigational Drugs of Brucella abortus in the L- and S-forms on the Subpopulations of Blood Cells and Peritoneal Fluid of White Mice (Communication 2). Epidemiology and Vaccinal Prevention. 2015;14(2):102-106. (In Russ.) https://doi.org/10.31631/2073-3046-2015-14-2-102-106

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ISSN 2073-3046 (Print)
ISSN 2619-0494 (Online)