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Anti-Diphtheria Antitoxic Immunity in the Population of Rostov-on-Don and the Rostov Region

https://doi.org/10.31631/2073-3046-2019-18-2-68-73

Abstract

The aim of the study was to assess the level of vaccination and the state of tension of diphtheria antitoxic immunity in the population. Materials and methods. The level of inoculation and the state of tension of anti-diphtheria antitoxic immunity were determined for the period 2013–2017 among the population of Rostov-on-Don and the Rostov region (children 3–4 years old (1075 people), teenagers 16–17 years old (1107 people), adults 18 and older (1818 people). Discussion. The vaccination coverage of the child population was 98.5–99.2%, adolescents – 98.8–99.8%, adults – 98.0–98.7%. When assessing the level of anti-diphtheria antitoxic immunity, it was established that the number of seropositive to diphtheria among children was 96.1 ± 0.6% of the examined, adolescents – 98.0 ± 0.4% of the examined, adults – 91.5 ± 0.6% of the examined. The highest indices of the level of antitoxic immunity to diphtheria, assessed by the number of both seropositive and persons with high antitoxin titers (82.3 ± 1.1% of the examined) were found among adolescents. The results of the serological monitoring of anti-diphtheria antitoxic immunity as a whole confirmed the data on the almost complete vaccination coverage of the population and indicated a high level of its tension. Conclusion. Vaccination and timely vaccination against diphtheria ensured a successful diphtheria situation in the region.

About the Authors

E. V. Kovalev
Office of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Rostov Region.
Russian Federation
Evgeniy V. Kovalev  – head (Chief State Doctor in the Rostov Region) of Department.


G. G. Kharseeva
Rostov State Medical University, Ministry of Healthcarre of Russia.
Russian Federation
Galina G. Kharseeva – Dr. Sci. (Med.), professor, head of the Department of Microbiology and Virology 2.


S. A. Nenadskay
Center of hygiene and epidemiology in the Rostov region.
Russian Federation
Svetlana A. Nenadskay  – head of Epidemiological Surveillance of Department of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Rostov Region.


A. M. Ryabova
Center of hygiene and epidemiology in the Rostov region.
Russian Federation
Alyona M. Ryabova – head of the Laboratory of Bacteriological and Parasitological Research.


E. L. Alutina
Rostov State Medical University, Ministry of Healthcarre of Russia.
Russian Federation
Elvira L. Alutina  – assistant of Department of Microbiology of Virology № 2.


I. S. Vorotnykova
Office of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Rostov Region.
Russian Federation
Irina S. Vorotnikova – chief specialist, Department of Epidemiological Surveillance Department.


G. A. Myroshnichenko
Office of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Rostov Region.
Russian Federation
Galina A. Miroshnichenko – deputy head of Epidemiological Surveillance of Department.


M. M. Shvager
Center of hygiene and epidemiology in the Rostov region.
Russian Federation
Mikhail M. Schwager – head of the Department of Epidemiology and Expertise.


M. Ya. Zanina
Center of hygiene and epidemiology in the Rostov region.
Russian Federation
Marina Y. Zanina  – deputy head of the Organization Department Department.


References

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Review

For citations:


Kovalev E.V., Kharseeva G.G., Nenadskay S.A., Ryabova A.M., Alutina E.L., Vorotnykova I.S., Myroshnichenko G.A., Shvager M.M., Zanina M.Ya. Anti-Diphtheria Antitoxic Immunity in the Population of Rostov-on-Don and the Rostov Region. Epidemiology and Vaccinal Prevention. 2019;18(2):68-73. (In Russ.) https://doi.org/10.31631/2073-3046-2019-18-2-68-73

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ISSN 2073-3046 (Print)
ISSN 2619-0494 (Online)