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Cholera Bengal: Epidemiological Monitoring and Genomic Analysis of Strains V. cholerae O139

https://doi.org/10.31631/2073-3046-2024-23-6-160-168

Abstract

Relevance. Major outbreaks, sporadic cases and intercontinental shipments of Bengal cholera caused by Vibrio cholerae O139 occurred from 1992 to 2018 in 26 countries, including 16 Asian countries.
Аim. To characterize the spread of Bengal cholera in the world, including in Russia, in relation to the properties of V. cholerae O139.
Results. Data on epidemic manifestations of Bengal cholera in the world, including in Russia, in relation to the phenotypic and molecular biological properties of V. cholerae O139 strains are presented. The evolution of their genome and the successive events of the introduction of V. cholerae O139 are described. Conclusion. The isolation of V. cholerae O139 from a patient with ctxAB+ gene, drug resistance to a number of antibiotics in China in 2023 indicates that the problem of Bengal cholera has been continued still in the modern period.

About the Author

E. A. Moskvitina
Federal State Health Care Institution "Rostov-on-Don Anti- plague Institute" of the Rospotrebnadzor
Russian Federation

Elsa A. Moskvitina – Dr. Sci. (Med.), Professor, Chief Researcher

Rostov-on-Don

+7 (863) 240-27-03



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Moskvitina E.A. Cholera Bengal: Epidemiological Monitoring and Genomic Analysis of Strains V. cholerae O139. Epidemiology and Vaccinal Prevention. 2024;23(6):160-168. (In Russ.) https://doi.org/10.31631/2073-3046-2024-23-6-160-168

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