Assessment of the Degree of Allergenic Effects of Various Drugs of Francisella tularensis
https://doi.org/10.31631/2073-3046-2017-16-5-58-61
Abstract
The evaluation of sensitization conducted on guinea pig leukocytes immunized with the cell wall preparations of F. tularensis. In this research was shown that the cell wall preparations F tularensis subsp mediaasiatica A-61 and F tularensis subsp tularensis В-399 A-Cole do not caused allergization in contrast with cell wall prepararions of F. tularensis 15 (extracted by Research Institute of Epidemiology and Hygiene) and F. tularensis subsp. holarctica 306.
About the Authors
T. P. Starovoitova
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
V. I. Dubrovina
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
T. A. Ivanova
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
A. V. Korneva
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
S. A. Vityazeva
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
M. Yu. Kotlov
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
S. V. Balakhonov
Irkutsk Antiplague Research Institute of Siberia and the Far East of Federal Service on Customers’ Rights Protection and Human WellBeing Surveillance
Russian Federation
Russian Federation
References
1. Pathophysiology of the immune system. Churilov L.P., Vasiljev A.G.: Saint Petersburg «Folliant». 2014: 664 (in Russian).
2. Nikolaev V.B. Physico-chemical and immunobiological properties of antigens of tularemic microbe. Doctorate of med. sci. diss. Irkutsk; 2005 (in Rissian).
3. Cellular and humoral immunity factors in the pathogenesis of tularemia. Ed.; S.V. Balakhonov. Irkutsk; 2017: 136 (in Russian).
4. Laboratory methods in clinic. Ed.: V.V. Men’shikov. Moscow; 1987; 365 (in Russian).
5. Firstova V.V. Experimental study immunological features a choice of strategy assessment of post-vaccination immunity against plague and tularemia. Doctorate of biol. sci. diss. Obolensk; 2015 (in Russian).
6. Kuznetsova E.M. Optimization methods for the preparation of antigenic complexes tularemic microbe and construction on their basis of diagnostic products: Doctorate of biol. sci. diss. Saratov; 2011 (in Russian).
7. Guidelines MU 3.1.2007-05. Prevention of infectious diseases. Epidemiological surveillance of tularemia (in Russian).
Review
For citations:
Starovoitova T.P., Dubrovina V.I., Ivanova T.A., Korneva A.V., Vityazeva S.A., Kotlov M.Yu., Balakhonov S.V. Assessment of the Degree of Allergenic Effects of Various Drugs of Francisella tularensis. Epidemiology and Vaccinal Prevention. 2017;16(5):58-61. (In Russ.) https://doi.org/10.31631/2073-3046-2017-16-5-58-61
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