Screening for ТВ Infection. State of the Problem
https://doi.org/10.31631/2073-3046-2016-15-1-28-33
Abstract
Introduction. Currently, the issue of early detection of tuberculosis infection in children with use as the primary method of tuberculin is extremely important. Against the background of the current debate about the effectiveness of TB infection immunodiagnostics the technique of posing skin tests using a skin prick test, developed and patented in the Samara State Medical University. Purpose. To optimize the screening immunodiagnostics of TB infection. Materials and methods. Were Mantoux tuberculin purified with the standard and the sample dilution 2mE prick test in 300 children aged 3 to 7 years. Results and conclusions. Compares the staging technique samples, the qualitative characteristics of the techniques and the results of tests with the help of ultrasound papules. The data show the advantages of the proposed method, the last registration and certification.
Keywords
иммунодиагностика,
кожные пробы,
туберкулез,
проба Манту,
прик-тест,
микобактерия туберкулеза,
туберкулинодиагностика,
иммунодиагностика,
туберкулезная инфекция,
immunodiagnostics,
skin test,
TB Mantoux test,
skin prick test,
Mycobacterium tuberculosis,
tuberculin,
immunodiagnostics,
TB-infection
About the Author
E. A. Borodulina
State Educational Institution of Higher Professional Training «Samara State Medical University», of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
References
1. Aksenova V.A. Topical issues of screening children for tuberculosis . Tuberculosis and Lung Disease. 2013; 3: 7-8 (in Russian).
2. Baryshnikovа L.A., Lebedeva N.O., Katkova L.I., Vdovenko S.A. et al. . The experience of the new technology for screening children and adolescents to TB infection in the Samara region . Tuberculosis and Lung Disease. 2012; 11: 27 – 31 (in Russian).
3. Gubkina M.F. New technologies in the diagnosis of tuberculosis in children and adolescents at risk . Tuberculosis and Lung Disease . 2011 ; 4: 112 (in Russian).
4. Kiselev V.I. A new skin test for the diagnosis of tuberculosis on the basis of recombinant protein ESAT-CFP. Molecular Medicine . 2008; 4: 4- – 6 (in Russian).
5. Aksenova V.A., Klevno N.I. Sevastyanova T.A. The epidemiological situation of tuberculosis in children and adolescents in Russia. Tuberculosis and Lung Disease. 2011; 4: 22 (in Russian).
6. . Nechayeva O.B. The epidemiological situation of tuberculosis among children in Russia. Tuberculosis and Lung Disease. 2013; 4: 62 (in Russian).
7. Slogotskaya L.V. Skin immunological tests for tuberculosis - history and modernity. Tuberculosis and Lung Disease. 2013; 5: 39 – 46 (in Russian).
8. Mitinskaya L.A. Tuberculin (lecture). Problems of tuberculosis. 1998; 3: 76 – 77 (in Russian).
9. Borodulin B.E., Borodulina E.A. Differential diagnosis of post-infectious tuberculin allergy in children with atopic diseases. Problems of tuberculosis. 2006;
10. 1: 9 – 13 (in Russian).
11. Order №109 of March 21, 2003. «On improvement of TB control in the Russian Federation». 2003; 55 – 62.
12. Available at: http://www.proza.ru/2013/11/09/649
13. Available at: http://www.vostokmedia.com/
14. Available at: http://vladmedicina.ru/
15. Available at: http://www.proza.ru/
16. Borodulina E.A., Borodulin B.E. Individual tuberculin skin prick test. Problems of Tuberculosis and Lung Disease. 2006; 3: 33-35 (in Russian).
17. Borodulina E.A. Prick-test in the diagnosis of tuberculin allergy. Allergology. 2005; 3: 34 – 35 (in Russian).
18. Amosova E.A., Borodulina E.A. Device for setting a tuberculin skin test. The patent for utility model number 83168; 2009 (in Russian).
19. Borodulina E.A., Pyatin V.F., Korolev V.V., Kozlova O.S., Amosova E.A. Tuberculin Mantoux test and by using the technique of «prick-test» and features autonomic balance in children when they are carrying out. Tuberculosis and Lung Disease. 2012; 89 (1): 39 – 43 (in Russian).
20. Borodulina E.A., Kozlova O.S., SeredinaY.P., Korolev V.V., Pyatin V.F., Amosova E.A. Features vegetative balance in tuberculin Mantoux method and using a skin prick-test. Kazan Medical Journal. 2012; 93 (3): 68 – 73(in Russian).
21. Borodulina E.A., Orlov E.V., Borodulin B.E., Tabashnikova A.I. Diagnosis of infection with Mycobacterium tuberculosis in children with atopic dermatitis. Monograph. Samara: «Ofort», Samara State Medical University Health Ministry of Russia; 2012 (in Russian).
22. Borodulina E.A., Borodulin B.E. et al. The apparatus for tuberculin test. Patent RU, 2139737 A61M 5/28; 2014 (in Russian).
Review
For citations:
Borodulina E.A. Screening for ТВ Infection. State of the Problem. Epidemiology and Vaccinal Prevention. 2016;15(1):28-33. (In Russ.) https://doi.org/10.31631/2073-3046-2016-15-1-28-33
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