Comparative Evaluation of Allergodiagnostic of Tuberculosis in Children
https://doi.org/10.31631/2073-3046-2016-15-3-41-44
Abstract
The comparative analysis of results of the tuberculin skin test (TST) and of the skin test with the recombinant tuberculosis allergen (Diaskintest - DST) in 7978 children with active tuberculosis revealed for the first time in 2013 - 2014 was carried out. The negative DST result and positive TST result are observed at 551 (6.91%) of patients. 92 patients (1.15%) had negative both tests, and at 98 people (1.23%) DST has yielded positive result, PM - negative. Other patients had positive both tests. In general, by means of DST tuberculosis initially hasn't been revealed at 643 (8.06%) patients, and by means of TST - at 190 (2.38%) patients. The difference is statistically reliable (t = 9.16; P < 0.05). Dynamics of tests results at patients with active tuberculosis was studied. The result of DST remained negative for a year in18.7% of patients, in 26,7% of patients with initially negative DST the result became positive in 3 months, in 2.7% - a year after the first testing. Tuberculosis of various forms and localizations, including TB+, was diagnosed for children with initially negative results of DST and positive TST.
About the Authors
I. V. Mikheeva
Federal Budget Institution of Science «Central Research Institute of Epidemiology» of The Federal Service on Customers ' Rights Protection and Human Well-being Surveillance
Russian Federation
Russian Federation
E. Yu. Burdova
Federal Budget Institution of Science «Central Research Institute of Epidemiology» of The Federal Service on Customers ' Rights Protection and Human Well-being Surveillance
Russian Federation
Russian Federation
A. A. Melnikova
Federal Budget Institution of Science «Central Research Institute of Epidemiology» of The Federal Service on Customers ' Rights Protection and Human Well-being Surveillance
Russian Federation
Russian Federation
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Review
For citations:
Mikheeva I.V., Burdova E.Yu., Melnikova A.A. Comparative Evaluation of Allergodiagnostic of Tuberculosis in Children. Epidemiology and Vaccinal Prevention. 2016;15(3):41-44. (In Russ.) https://doi.org/10.31631/2073-3046-2016-15-3-41-44
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