Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
https://doi.org/10.31631/2073-3046-2018-17-1-20-24
Abstract
This article presents the results of a simple, blind, randomized, placebo-controlled, single-center, prospective research of the reactogenicity, safety, and immunogenicity of the domestic influenza inactivated split vaccine «Flu-M» in immunization of the adult population of 18–60 years old. Low reactogenicity, high safety profile and immunogenicity of the Flu-M vaccine were determined.
About the Authors
I. V. Fel'dblyum
Federal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
S. D. Novgorodova
Federal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
G. M. Ignat'ev
The Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological Agency
Russian Federation
Russian Federation
S. O. Golodnova
Federal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
V. P. Trukhin
The Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological Agency
Russian Federation
Russian Federation
S. Ya Melnikov
The Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological Agency
Russian Federation
Russian Federation
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Review
For citations:
Fel'dblyum I.V., Novgorodova S.D., Ignat'ev G.M., Golodnova S.O., Trukhin V.P., Melnikov S.Ya. Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years. Epidemiology and Vaccinal Prevention. 2018;17(1):20-24. (In Russ.) https://doi.org/10.31631/2073-3046-2018-17-1-20-24
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